高等学校化学学报 ›› 1995, Vol. 16 ›› Issue (7): 1051.

• 论文 • 上一篇    下一篇

金属卟啉的合成及其对细胞色素P-450的模拟(ⅪⅤ)--钴卟啉对环己烷的单充氧催化作用

陈新斌, 郭灿城, 梁本熹, 饶宗海, 杨治国   

  1. 湖南大学化学化工系, 长沙, 410082
  • 收稿日期:1994-07-13 修回日期:1995-01-27 出版日期:1995-07-24 发布日期:1995-07-24
  • 通讯作者: 郭灿城
  • 作者简介:陈新斌,男,33岁,讲师.
  • 基金资助:

    国家自然科学基金

Studies on the Syntheses of Metalloporphyrins and Biomimesis for Cytochrome P-450(XIV)--Catalysis of TPPCo(Ⅱ) for Cyclohexane Monooxygenation

CHEN Xin-Bin, GUO Can-Cheng, LIANG Ben-Xi, RAO Zong-Hai, YANG Zhi-Guo   

  1. Department of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082
  • Received:1994-07-13 Revised:1995-01-27 Online:1995-07-24 Published:1995-07-24

摘要: 报道了钴卟啉催化下PhIO对环己烷的单充氧反应及其反应动力学行为。探讨了反应温度和有机配体对该反应的影响。研究结果表明:在配体吡啶的作用下,钴卟啉对PhIO单充氧化环己烷具有催化活性,其催化性能与反应温度以及吡啶用量有关。反应速率随温度增加而增加,且表观反应速率常数与反应温度之间存在Arrhenius关系。反应产率随温度升高而降低。当吡啶与TPPCo(Ⅱ)用量为50:1时,TPPCo(Ⅱ)催化效果最好。

关键词: 卟啉, 催化, 氧化反应, 温度效应

Abstract: This paper reports the catalysis of TPPCo(Ⅱ) for cyclohexane monooxygenation with PhIO. The kinetic properties, the temperature effect and the effect of axial ligands of the reactions were studied. The results show that TPPCo(Ⅱ) with axial ligand pyridine can catalyze cyclohexane monooxygenation with PhIO and that the catalytic properties are related to the reaction temperature and the quantity of pyridine. The rates of the reactions can increase with the increase of the reaction temperature. There is Arrhenius relationship between the rate constants of the reactions and the reaction temperature. The yields of the products decrease with the increase of the reaction temperature. The catalytic effect of TPPCo(Ⅱ) is the best when the quantity of pyridine is 50 times that of TPPCo(Ⅱ).

Key words: Porphyrin, Catalysis, Oxidation reaction, Temperature effect

TrendMD: