高等学校化学学报

高等学校化学学报 ›› 1993, Vol. 14 ›› Issue (4): 466.

• 研究快报 • 上一篇    下一篇

金属硫蛋白的聚合反应动力学

张保林1, 任宏伟2, 王文清2   

  1. 1. 南京大学配位化学国家重点实验室, 南京 210008;
    2. 北京大学技术物理系, 北京 100871
  • 收稿日期:1992-11-12 修回日期:1992-12-28 出版日期:1993-04-24 发布日期:1993-04-24
  • 通讯作者: 张保林
  • 基金资助:

    国家863-103-21-09资助

Polymerizational Kinetics of Metallothionein

ZHANG Bao-Lin1, REN Hong-Wei2, WANG Wen-Qing2   

  1. 1. Coordination Chemistry State Key Laboratory, Nanjing University, Nanjing, 210008;
    2. Technical Physics Department of Peking University, Beijing
  • Received:1992-11-12 Revised:1992-12-28 Online:1993-04-24 Published:1993-04-24

PDF (PC)

被引次数

4

关键词: 金属硫蛋白, 聚合, 动力学

Abstract: Chromatographic separation of the aqueous solutions of rabbit hepatic (Cd,Zn)7MTin50 mmol/Lsodium phosphate (pH 7.40) after storing for various time was performed on HPLCin an attempt to investigate the thermodynamic stability of the Metallothionein (MT) solution.It was found that MTcould polymerize slowly by itself.Assuming the polymerization only occurs from monomer to dimer, an apparent bimolecular rate constant of the order of 10-3(mol/L)-1·/day-1 at 4℃ was obtained.The results also clearly reveal that the isoform MT-2 can polymerize more easily than MT-1.

Key words: Metallothionein, Polymerization, Kinetics

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