高等学校化学学报

高等学校化学学报 ›› 1996, Vol. 17 ›› Issue (10): 1565.

• 论文 • 上一篇    下一篇

4-羟基-3-酰基(酯基)-2H-1,2-苯并噻嗪-1,1-二氧化物衍生物的合成及生物活性

赵国锋, 杨华铮, 王玲秀   

  1. 南开大学元素有机化学研究所, 天津, 300071
  • 收稿日期:1995-10-29 出版日期:1996-10-24 发布日期:1996-10-24
  • 通讯作者: 杨华铮
  • 作者简介:赵国锋,男,28岁,博士.
  • 基金资助:

    国家自然科学基金

Studies on the Synthesis and Biological Activity of the Derivatives of 4-Hydroxyl-3-acyl (alkoxylcarbonyl)-2H-1,2-benzothiazine-1,1-dioxides

ZHAO Guo-Feng, YANG Hua-Zheng, WANG Ling-Xiu   

  1. Institute of Elemento-Organic Chemistry Nankai University, Tianjin, 300071
  • Received:1995-10-29 Online:1996-10-24 Published:1996-10-24

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摘要： 利用4-羟基-3-酰基(酯基)-2H-1,2-苯并噻嗪-1,1-二氧化物分别与芳基异氰酸酯、苯肼、氯甲酸甲酯和乙二醇反应合成了20种新衍生物,研究了其与异氰酸酯在不同摩尔比碱作用下的加成反应。生物活性测定结果表明,大部分化合物具有较好的除草活性和植物生长调节活性。

关键词: 合成, 2H-1, 2-苯并噻嗪-1, 1-二氧化物, 除草活性, 植物生长调节活性

Abstract: In this paper 20 new derivatives were synthesized by the reaction of 4-hydroxyl-3-acyl(alkoxylcarbonyl)-2H-1,2-benzothiazine-1,1-dioxides(Ⅱa-c) with aryl isocyanates,phenyl hydrazine,methyl chloroformate and ethylene glycol,and the reaction of compounds Ⅱa-c with aryl isocyanates was studied under the different molar ratios of strong base NaH.Their structures were characterized by 1H NMR,IRand elementary analysis.The biological tests indicated that the majority showed good herbicidal activity and plant-growth regulating activity.

Key words: Synthesis, 2H-1,2-Benzothiazine-1,1-dioxide, Herbicidal activity, Plant-growth regulating activity

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