关键词: &beta, -取代丙烯酸酯(酰胺), 杀菌剂, 合成

Abstract: β-methoxyl acrylate esters are a new type of fungicides appeared recently. By summarizing the relationship of the structure and bioactivity of this type of synthesized fungicides, we proposed that by changing the ester group and β-group of β-substituted acry-late esters, the fungicidal activity of this type of compounds would be increased. Twenty-two β-aroxylethoxyl acrylate esters and eight β-methoxyl acrylate amides were synthesized. In the synthesis of the target products, when the carbon-increasing regent is ethyl formate instead of methyl formate, the analogues ethyl β-aroxyethoxy acrylate were obtained instead of the methyl esters. There's a ester-exchanging process in the reactions, the mechanism of which had been proposed. The preliminary bio-assay indicated that these new compounds possessed some fungicidal activities. The bio-assay also indicated that these new compounds showed different activities on sensitive fungi and the fungi with resistance.

Key words: β-Substituted acrylated(amides), Fungicides, Synthesis