高等学校化学学报

高等学校化学学报 ›› 1996, Vol. 17 ›› Issue (8): 1188.

• 研究简报 • 上一篇    下一篇

Keggin结构钨磷酸稀土镨盐杂多蓝的合成及抗艾滋病病毒(HIV-1)活性的研究

刘术侠1, 刘彦勇1, 王恩波1, 曾毅2, 李泽琳2   

  1. 1. 东北师范大学化学系, 长春 130024;
    2. 中国预防医学科学院, 北京
  • 收稿日期:1995-08-21 出版日期:1996-08-24 发布日期:1996-08-24
  • 通讯作者: 王恩波
  • 作者简介:刘术侠,女,31岁,博士研究生,讲师.
  • 基金资助:

    国家自然科学基金;中国科学院长春应用化学研究所稀土化学与物理开放实验室资助

Synthesis of Heteropoly Blue of Praseodymium Tungstophosphte with Keggin Structure and Studies on Their Anti-HIV Activity

LIU Shu-Xia1, LIU Yan-Yong1, WANG En-Bo1, ZENG Yi2, LI Ze-Lin2   

  1. 1. Department of Chemistry, Northeast Normal University, Changchu 130024;
    2. Chinese Academy of Preventive Medicine, Beijing
  • Received:1995-08-21 Online:1996-08-24 Published:1996-08-24

PDF (PC)

被引次数

131

关键词: 稀土, 钨磷杂多蓝, 合成, 抗艾滋病病毒(HIV-1)活性

Abstract: e-and 4e-Heteropoly bule compounds of praseodymium tungstophosphate with Keggin structure were synthesized for the first time using control-potential electrolysis method, IR, UV-Vis and 31P NMRspectra were used to characterize their structures.The test of checking proliferation of MT-4 cells and their anti-HIVactivities show that these heteropoly blue compounds of praseodymium salts with Keggin structure have fairly low cell toxicity and relatively high anti-HIVactivity, The TI50 of Pr(2)and Pr(4)are 66 and 70,which demonscrate that their anti-HIVactivities are better than those of PM-29.

Key words: Tungstophosphrie heteropoly blue, Praseodymium salt, Synthesis, Anti-HIV activity

TrendMD: