高等学校化学学报 ›› 1996, Vol. 17 ›› Issue (10): 1578.

• 论文 • 上一篇    下一篇

含有二氢吡唑环的新三唑类化合物的设计与合成

史延年, 杨扬, 方建新, 吕文硕   

  1. 南开大学元素有机化学研究所, 天津, 300071
  • 收稿日期:1995-07-07 出版日期:1996-10-24 发布日期:1996-10-24
  • 通讯作者: 杨扬
  • 作者简介:史延年,男,64岁.教授.
  • 基金资助:

    国家自然科学基金

Studies on Design and Synthesis of New Triazole Compounds Containing 2H-Pyrazole

SHI Yan-Nian, YANG Yang, FANG Jian-Xin, LU Wen-Shuo   

  1. Inst.of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071
  • Received:1995-07-07 Online:1996-10-24 Published:1996-10-24

摘要: 设计并合成了10种含有二氢吡唑环的新三唑类化合物。对新化合物结构进行了确证,讨论了二氢吡唑环的成环方式,所合成的化合物均具有一定的生物活性。

关键词: 三唑, 二氢吡唑, 合成

Abstract: Ten new derivatives of new triazole compounds which contain the ring of 2H-pyrazole were designed and synthesized.The structures of new compounds were confirmed by 1H NMR,IR,MS and elemental analysis.The way and mechanism of the reaction ofα,β-unsaturated ketone and phenylhydrazine were also discussed.The results of bioassay indicate that each compounds has some biological activities.

Key words: 1,2,4-Triazole, 2H-Pyrazole, Synthesis

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