高等学校化学学报 ›› 1995, Vol. 16 ›› Issue (12): 1888.

• 论文 • 上一篇    下一篇

1-(取代吡唑-4-基)-1,2,4-三唑的合成及生物活性研究

黄震年, 李正名   

  1. 南开大学元素有机化学研究所, 天津, 300071
  • 收稿日期:1994-12-26 修回日期:1995-07-29 出版日期:1995-12-24 发布日期:1995-12-24
  • 通讯作者: 李正名
  • 作者简介:黄震年,男,30岁 .博士研究生.
  • 基金资助:

    国家自然科学基金

Synthesis and Biological Activities of 1-(Substituted Pyrazol-4-yl)-1,2,4-triazoles

HUANG Zhen-Nian, LI Zheng-Ming   

  1. Institute of Elemento-Organic Chemistry, Nankai university, Tianjin, 300071
  • Received:1994-12-26 Revised:1995-07-29 Online:1995-12-24 Published:1995-12-24

摘要: 合成了23个新的1-(取代吡唑-4-基)1,2,4-三唑化合物,经EA、IR、1HNMR和MS确定其组成和结构,并对其进行了抑菌及生长调节活性的初步观察。

关键词: 合成, 1-(取代吡唑-4-基)-1,2,4-三唑, 生物活性

Abstract: Twenty three novel heterocyclic compounds with the following general formula as Follows:R:C6H5,4-ClC6H4,4-CH3OC6H4,4-CH3C6H4,4-BrC6H4,t-C4H9;R1:SCH3,NHAr'(Ar′:4-CH3C6H1,2-CH3OC6H1,4-ClC6H4):R2:C6N5.have been prepared with α-oxo-α-(1,2,4-triazol-1-yl)ketene dithioacetals as intermediates,and their structures were proved by elementary analyses and spectral methods.Preliminary bioassay show that some of these compounds have plant-regulatory activities.

Key words: Synthesis, 1-(Substituted pyrazol-4-yl)-1,2,4-triazole, Biological activities

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