高等学校化学学报

高等学校化学学报 ›› 1991, Vol. 12 ›› Issue (6): 780.

• 论文 • 上一篇    下一篇

有机锗倍半氧化物及倍半硫化物的合成

孙丽娟, 吴煜升, 白明章   

  1. 南开大学元素有机化学研究所, 天津, 300071
  • 收稿日期:1990-03-28 出版日期:1991-06-24 发布日期:1991-06-24
  • 通讯作者: 孙丽娟

The Syntheses of Organogermanium Sesquioxides and Sesquisulfides

Sun Li-juan, Wu Yu-sheng, Bai Ming-zhang   

  1. Institute of Elemento-Organic chemistry, Nankai University, Tianjin, 300071
  • Received:1990-03-28 Online:1991-06-24 Published:1991-06-24

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被引次数

8

摘要： 有机锗化合物具有广谱药理活性,特别是抗肿瘤活性,其中有机锗倍半氧化物和倍半硫化物具有显著的抗癌活性。在我国这方面的研究却很少,为进一步研究有机锗的药理活性,我们合成了未见报道的一系列有机锗倍半氧化物和倍半硫化物,并分离了它们的中间体。

关键词: 有机锗倍半氧化物, 倍半硫化物, 生物活性, 合成

Abstract: Eight new organogermanium sesquisulfides and sesquioxides were synthesized by improved method and their intermediates were also separated. The structures of these compounds were identified by elemental analysis, IR, and 13CNMR determination. The inhibition of the compounds SG-f, SG-h against IMC carcinoma was significant.

Key words: Organogermanium sesquioxides, Sesquisulfide, Bioactivity, Synthesis

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