高等学校化学学报

高等学校化学学报 ›› 1989, Vol. 10 ›› Issue (3): 254.

• 研究论文 • 上一篇    下一篇

α-氨基膦(次膦)酸类衍生物的合成及其性质

杨华铮, 王建武, 程慕如, 王玲秀, 张玉芬   

  1. 南开大学元素有机化学研究所
  • 收稿日期:1987-10-18 出版日期:1989-03-24 发布日期:1989-03-24
  • 通讯作者: 杨华铮
  • 基金资助:

    国家自然科学基金

Studies on the Synthesis and Properties of a-Amino Phospho(i)nic Acids

Yang Huazheng, Wang Jianwu, Cheng Muru, Wang Lingxiu, Zhang Yufen   

  1. Institute of Elemento-Organic Chemistry, Nankai University, Tianjin
  • Received:1987-10-18 Online:1989-03-24 Published:1989-03-24

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摘要： 采用8种合成方法,合成了38种α-氨基膦(次膦)酸类衍生物。发现部分α-氨基膦酸化合物中含有1个结晶水。测定了化合物的pKα值。所有化合物都具有一定除草和杀菌活性。

关键词: &alpha, -氨基膦(次膦)酸, 合成, 结晶水, pK&alpha, 值, 除草及杀菌活性

Abstract: 38 Derivatives of a-amino phospho(i)nic acids(RCH(NH2)-P(O)-(OH)R',R,R'=alkyl or aryl) have been synthesized by the addition reaction of the phosphorous compounds containing P-H bond to imine compounds in which the imino group was protected with actyl or carbobenzyloxy group. The products could be purified by recrystallization, ion exchange technique or repeated acid-base neutralization. Some of the a-amino phosphonic acids contain one moleculer of water when they were recrystallized from a mixture of alcohol and water. The pKavalues of the title compounds have been measured. It has been found that all of these compounds have herbicidal and fungicidal activities.

Key words: a-Amino phospho(i)nic acid, Synthesis, Crystal water, pKa, Herbicidal and fungicidal activities

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