Integrated Microfluidic Chip System with Gravity Driven Multiphase Laminar Flow Separation and Ion Selective Electrode Detection

Abstract

Abstract: A microfluidic chip based on multiphase laminar flow separation coupled to ion selective electrode detection was developed for the first time. The system was applied to the determination of potassium in serum,employing a multiphase laminar flow approach for separation of potassium ions from the serum matrix by diffusion into a buffer acceptor stream. Both sample and acceptor streams were driven by gravity,and potassium was determined by using an ion selective electrode integrated on the chip.

Key words: Microfluidic chip, Multiphase laminar flow separation, Gravity driving, Ion selective electrode

CLC Number:

O657

TrendMD:

CHEN Hong, FANG Qun, YIN Xue-Feng, FANG Zhao-Lun . Integrated Microfluidic Chip System with Gravity Driven Multiphase Laminar Flow Separation and Ion Selective Electrode Detection[J]. Chem. J. Chinese Universities, 2004, 25(8): 1428.

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Integrated Microfluidic Chip System with Gravity Driven Multiphase Laminar Flow Separation and Ion Selective Electrode Detection

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