高等学校化学学报

高等学校化学学报 ›› 2005, Vol. 26 ›› Issue (8): 1459.

• 研究论文 • 上一篇    下一篇

苯环2-位不同酯基取代的磺酰脲类化合物的合成及其除草活性

李鹏飞, 马宁, 王宝雷, 李正名, 王素华, 李永红   

  1. 南开大学元素有机化学研究所, 元素有机化学国家重点实验室, 天津300071
  • 收稿日期:2004-08-30 出版日期:2005-08-10 发布日期:2005-08-10
  • 通讯作者: 李正名(1931年出生),男,教授,博士生导师,中国工程院院士,从事有机化学和农药化学领域的研究.E-mail:nkzm l@nk.sina.net E-mail:nkzm l@nk.sina.net
  • 基金资助:

    国家“九七三”计划项目(批准号:2003CB114406);天津市自然科学重点基金(批准号:033803411)资助.

Synthesis and Herbicidal Activity of New Sulfonylurea Derivatives

LI Peng-Fei, MA Ning, WANG Bao-Lei, LI Zheng-Ming, WANG Su-Hua, LI Yong-Hong   

  1. State Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China
  • Received:2004-08-30 Online:2005-08-10 Published:2005-08-10

PDF (PC)

被引次数

16

摘要： 以正在开发的磺酰脲类超高效除草剂NK94827[N'-(4'-甲基嘧啶-2'-基)-2-甲氧羰基苯磺酰脲]的基本结构为基础,设计合成了18个苯环2位不同酯基取代的的新型磺酰脲类化合物,产物结构均经1HNMR及元素分析确证.经油菜平皿法和盆栽试验测试除草活性,所合成的部分磺酰脲化合物的除草活性高.

关键词: 磺酰脲, 合成, 除草活性

Abstract: In order to search for more environmental-benign sulfonylurea herbicides and study their structure-activity relationship, on the basis of a new sulfonylurea herbicide NK94827 {N-[(4'-methyl)pyrimidin-2'-yl]-2-methoxycarbonyl phenylsulfonylurea}, 18 novel sulfonylurea compounds modified at benzoic acid ester were synthesized. The structures of the target compounds were confirmed by 1HNMR and elemental analysis. Preliminary herbicidal activity of these new sulfonylurea compounds was determined by rape disc assay and pot bioassay experiments. The results indicate that some compounds have good a herbicidal activity, and large lipophilic groups in ester moiety are unfavorable for the activity.

Key words: Sulfonylurea, Synthesis, Herbicidal activity

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