高等学校化学学报 ›› 2005, Vol. 26 ›› Issue (4): 631.

• 研究简报 • 上一篇    下一篇

二聚体有机锡配合物{[n-Bu2SnO2CCH(CS2NEt2)2]2O}2的合成、表征及晶体结构

尹汉东, 薛绳才, 王其宝   

  1. 聊城大学化学化工学院, 聊城 252059
  • 收稿日期:2004-03-16 出版日期:2005-04-10 发布日期:2005-04-10
  • 通讯作者: 尹汉东(1956年出生),男,教授,从事金属有机化学研究.E-mail:handongyin@lctu.edu.cn E-mail:handongyin@lctu.edu.cn
  • 基金资助:

    国家自然科学基金(批准号:20271025);山东省自然科学基金(批准号:L2003B01)资助.

Synthesis, Characterization and Crystal Structure of Dimer Organotin Complex {[n-Bu2SnO2CCH(CS2NEt2)2]2O}2

YIN Han-Dong, XUE Sheng-Cai, WANG Qi-Bao   

  1. Department of Chemistry, Liaocheng University, Liaocheng 252059, China
  • Received:2004-03-16 Online:2005-04-10 Published:2005-04-10

关键词: 有机锡配合物, 双(N, N-二乙基二硫代甲氨酰)乙酸, 合成, 晶体结构, 生物活性

Abstract: The title complex {[nBu2SnO2CCH(CS2NEt2)2]2O}2 was synthesized and characterized by elemental analysis, IR, NMR and Xray single crystal diffraction. The results show that the complex belongs to a monoclinic system with space group C2/c, and unit cell dimensions: a=2.848(5) nm, {b=1.381(2) nm}, c=3.239(6) nm, β=111.11(2)°, Z=4, V=11.884(35) nm3, D-c=1.329 g/cm3, {F(000)}=4 912, S=0.991, R-1=0.053 5, wR2=0.116 6. The complex has a centrosymmetric dimer structure mode with a fourmembered central endocyclic Sn2O2 unit. The endocyclic tin atoms are sixcoordination and have coordition geometry of distorted octahedron. The exocyclic tin atoms are fivecoordination and have coordination geometry of distorted trigonal bipyramid. This complex was tested in vitro against human tumour cell lines, MCF-7 and WiDr, and displayed the higher activity.

Key words: Organotin complex, Bis(N,N-diethyldithiocarbamyl)acetate}, Synthesis, Crystal structure, Biological activity

中图分类号: 

TrendMD: