高等学校化学学报 ›› 2003, Vol. 24 ›› Issue (4): 639.

• 论文 • 上一篇    下一篇

多羰基甾酮的选择性还原反应研究

崔建国1, 曾陇梅2, 苏镜娱2   

  1. 1. 广西师范学院化学系, 南宁 530001;
    2. 中山大学化学与化学工程学院, 广州 510275
  • 收稿日期:2002-03-15 出版日期:2003-04-24 发布日期:2003-04-24
  • 通讯作者: 曾陇梅(1931年出生),男,教授,博士生导师,主要从事天然产物化学研究.E-mail:ceszlm@zsu.edu.cn E-mail:ceszlm@zsu.edu.cn
  • 基金资助:

    国家自然科学基金(批准号:29932030);广东省自然科学基金(批准号:970154)资助

Selective Reductions of Steroidal Ketones with Keto-groups in the Nucleus and Side-chain

CUI Jian Guo1, ZENG Long Mei2, SU Jing Yu2   

  1. 1. Department of Chemistry, Guangxi Teachers College, Nanning 530001, China;
    2. School of Chemistry and Chemical Engineering, Zhongshan University, Guangzhou 510275, China
  • Received:2002-03-15 Online:2003-04-24 Published:2003-04-24

摘要: 在不同金属离子存在下,多羰基甾酮的甾核及支链上都发生了羰基与硼氢化钠的还原反应,得到具有不同的区域选择性和立体选择性的还原产物.

关键词: 多羰基甾酮, 还原反应, 区域选择性, 立体选择性

Abstract: On the study of reduction of some steroidal ketones with keto groups in the nucleus and side chain, it was found that the reduction with NaBH4 CH3OH, in the presence of different kind of metal ions such as Cd2+, Co2+, Ce3+ etc., may lead to different regio and stereo selective results and obtain different products.

Key words: Steroidal ketones, Reductive reaction, Regio selectivity, Stereo selectivity

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