高等学校化学学报

高等学校化学学报 ›› 2001, Vol. 22 ›› Issue (5): 768.

• 研究论文 • 上一篇    下一篇

3-取代苯甲酰氨基-2-硫代-2,4-噻唑烷二酮类衍生物的新合成法

褚长虎1, 许鹏飞1, 惠新平1, 张自义1, 廖仁安2, 李之春2   

  1. 1. 兰州大学化学化工学院, 应用有机化学国家重点实验室, 兰州 730000;
    2. 南开大学元素有机化学国家重点实验室, 天津 300071
  • 收稿日期:2000-03-14 出版日期:2001-05-24 发布日期:2001-05-24
  • 通讯作者: 张自义(1933出生),男,教授,博士生导师,从事杂环及杂原子化学研究.E-mail:yaolq@lzu.edu.cn E-mail:yaolq@lzu.edu.cn

New Method for Synthesis of 4-Substituted Benzamido-2-thioxo-2,4-thiazolidindiones

CHU Chang-Hu1, XU Peng-Fei1, HUI Xin-Ping1, ZHANG Zi-Yi1, LIAO Ren-An2, LI ZhI Chun2   

  1. 1. National Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China;
    2. State Key Laboratory of Elemento-organic Chemistry, Nankai University, Tianjin 300071, China
  • Received:2000-03-14 Online:2001-05-24 Published:2001-05-24

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被引次数

5

摘要： 通过简便的路线合成了8个3-取代苯甲酰氨基-2-硫代-2,4-噻唑烷二酮衍生物,并对其反应机理进行了讨论.所有化合物的结构均经元素分析、1HNMR、IR和MS谱确认.初步的生物活性测试结果表明,代表化合物表现出良好的抗菌活性和植物生长调节活性.

关键词: 2-硫代-2, 4-噻唑烷二酮, 合成, 机理, 生物活性

Abstract: Eight 3-substituted benzamido-2-thioxo-2,4-thiazolidindione derivatives 2a-2h were synthesized and the reaction mechanism was also discussed. The structures of these compounds were confirmed by elemental analyses and spectra data. The preliminary biological test showed that the representative compounds exhibited moderate antifungal and plant growth regulatory activities.

Key words: Thioxo-2,4-thiazolidindione, Synthesis, Mechanism, Biological activities

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