高等学校化学学报

高等学校化学学报 ›› 1997, Vol. 18 ›› Issue (9): 1438.

• 论文 • 上一篇    下一篇

邻苯三酚自氧化反应的动力学研究

袁倬斌, 高若梅   

  1. 中国科学技术大学研究生院, 北京 100039
  • 收稿日期:1996-08-12 出版日期:1997-09-24 发布日期:1997-09-24
  • 通讯作者: 袁悼斌, 男, 59岁, 教授, 博士导师.
  • 作者简介:袁悼斌, 男, 59岁, 教授, 博士导师.
  • 基金资助:

    国家自然科学基金;中国科学院长春应用化学研究所电分析化学开放实验室基金

Kinetics and Mechanism of Pyrogallol Autoxidation

YUAN Zhuo-Bin, GAO Ruo-Mei   

  1. Graduate School, University of Science and Technology Of China, Beijing 100039
  • Received:1996-08-12 Online:1997-09-24 Published:1997-09-24

PDF (PC)

被引次数

95

摘要： 利用单扫示波极谱法(并辅以紫外-可见光谱法)研究了邻苯三酚在pH7.20～9.10的Tris－HCl缓冲体系中自氧化反应的动力学.结果表明, 在过量溶解O2存在时, 反应对邻苯三酚为一级.在一定pH范围内, 准一级反应表现速率常数Kapp随pH值的增加而增加, 说明H2PYR-比H3PYR对溶解O2具有更高的反应活性.探讨了邻苯三酚自氧化生成半醒自由基和活性氧的反应机理, 用速率方程解释了实验现象.并为酶活力测定和药物抗氧活性研究提供了一种新方法.

关键词: 邻苯三酚自氧化, 单扫示波极谱法, 计算机拟合, 动力学

Abstract: The kinetics of pyrogallol autooxidation has been studied by single-sweeposcillopolarography in Tris-HCIbuffer soluton in the PHrange 7. 20-9. 10. The reaction wasfirst order to pyrogallol in the presence of excess dissolved O2. The focus was put onpyrogallol autooxidation with products of semiquinone free radical and active oxygen. Amechanism was presented which explains the increase in rate with increasing PHby postulating thatH2PYR-has a greater reactivity with dissolved O2 than H3PYR. The derived rate law is ingood agreement with the experimental observations. The paper also presented a new assayfor superoxlde dismutase and antioxidant activity of pharmaceuticals.

Key words: Pyrogallol autooxidation, Single-sweep oscillopolarography, Computer simulation, Kinetics

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