高等学校化学学报

高等学校化学学报 ›› 1991, Vol. 12 ›› Issue (1): 39.

• 论文 • 上一篇    下一篇

1-苯基-3-(3'-吲哚基)-5-取代苯基-2-吡唑啉的合成及1H NMR和MS中的取代基效应

刘志杰, 张建恒, 姜林   

  1. 西北大学化学系, 710069
  • 收稿日期:1989-05-29 出版日期:1991-01-24 发布日期:1991-01-24
  • 通讯作者: 刘志杰
  • 基金资助:

    国家自然科学基金

The Synthesis of 1-Phenyl-3-(3 '-Indolyl)-5-Substituted Phenyl-2-Pyrazolines and Their Substituent Effects in 1HNMR, MS

Liu Zhi-jie, Zhang Jian-heng, Jiang Lin   

  1. Department of Chemistry, Northwestern University, Xi'an, 710067
  • Received:1989-05-29 Online:1991-01-24 Published:1991-01-24

PDF (PC)

摘要： J-(3'-吲哚基)-3-取代苯基-2-丙烯-1-酮与茉肼反应,合成了10种新的1-苯基-3-(3'-吲哚基)-5-取代苯基-2-吡唑啉衍生物,其结构通过各种波谱证实.讨论了此系列化合物1HNMR和Ms中的取代基效应,得出取代基常数σ或σ+与质子化学位移,碎片相对丰度之间存在着良好的线性关系.

关键词: 吲哚, 吡唑啉, 合成, 取代基效应

Abstract: 10 new l-phenyl-3-(3'-indolyl)-5-substituted phenyl-2-pyrazolines were synthesized by the reactions of phenylhydrazine with 1-(3'-indolyl)-3-substituted phenyl-2-propen-l-ones. The structures of pyrazolines have been confirmed by their elementary analysis and spectral analysis. Agood linear relationship between σHand σ,(σm)in 1HNMR or the lg(KR/KH) and σ(σ+) in MS was discussed.

Key words: Indole, Pyrazoline, Synthesis, Substituent effect

TrendMD: