The Properties and Preparation of Crosslinked Chitosan Films

Abstract

Abstract: The crosslinked chitosan films were prepared with epichlorohydrin as a crosslinking agent, and characterized by FTIR, X-ray diffraction and SEM. Their mechanical properties were measured. The structure analysis indicated that at low temperature, the crosslinking reaction only occurred between -NH₂ group of chitosan and epichlorohydrin. When the temperature was above 40 ℃, -OHgroup of chitosan reacted with epichlorohydrin. The results from SEMand measurement of mechanical properties showed that the tensile strength of the crosslinked films was considerably improved, and the rate of degradation of crosslinked films by lysozyme was reduced. The new crosslinked chitosan films are expected to be used as controllable degradation biomaterials.

Key words: Chitosan, Epichlorohydrin, Crosslinked chitosan film, Mechanical properties, Lysozyme degradation

CLC Number:

O636.1

TrendMD:

ZHENG Hua, DU Yu-Min, YU Jia-Hui, XIAO Ling . The Properties and Preparation of Crosslinked Chitosan Films[J]. Chem. J. Chinese Universities, 2000, 21(5): 809.

[1]	XIA Wu, REN Yingyi, LIU Jing, WANG Feng. Chitosan Encapsulated CdSe QDs Assemblies for Visible Light-induced CO₂ Reduction in an Aqueous Solution [J]. Chem. J. Chinese Universities, 2022, 43(7): 20220192.
[2]	WANG Mingxia, LIU Zhihui, ZHU Zhen, LI Lingfeng, WANG Bowei. Preparation and Properties of Nano Lithium Magnesium Silicate-chitosan-sodium Alginate Composite Scaffold Materials [J]. Chem. J. Chinese Universities, 2021, 42(10): 3240.
[3]	WANG Bowei, MA Rui, WU Fan, LIU Zhihui, LI Lingfeng, ZHANG Xiao, LIU Dingkun, YANG Nan, LI Meihui, YANG Defeng, SUN Qi. Preparation and Characterization of Graphene Oxide-sodium Alginate-chitosan Composite Scaffold [J]. Chem. J. Chinese Universities, 2020, 41(9): 2099.
[4]	CAO Meng, LIU Yang, ZHANG Shangxi, WANG Zhenxi, XU Sheng. Synthesis and Photocatalytic Hydrogen Evolution Properties of Chitosan Cobalt Complex ^† [J]. Chem. J. Chinese Universities, 2020, 41(4): 735.
[5]	WANG Ruanfeng,YAN Shifeng,HU Zhen,YIN Jingbo. Preparation and Properties of CS/nHA Porous Composite Scaffold Based on In-situ Precipitation Method^† [J]. Chem. J. Chinese Universities, 2019, 40(5): 1080.
[6]	YIN Maoli,WANG Yingfeng,REN Xuehong. Preparation of Modified Chitosan Antibacterial Nanospheres^† [J]. Chem. J. Chinese Universities, 2019, 40(1): 173.
[7]	DING Lingyun, JU Yuanlai, SUN Wei, CHEN Ji. Preparation of Functional Patterned Protein Arrays via the Combination of Inverse Emulsion and Breath Figure Method^† [J]. Chem. J. Chinese Universities, 2018, 39(6): 1311.
[8]	LIU Zhihui,QIU Tianyuan,DU Liuyi,YANG Junxing,LIU Kang,WANG Bowei. Preparation and Characterization of Chitosan Alginate Plastic Scaffolds^† [J]. Chem. J. Chinese Universities, 2018, 39(5): 1105.
[9]	LI Hui, XING Zhe, LI Rong, ZHANG Mingxing, WANG Minglei, TAN Yizhe, WU Guozhong. Preparation of Cu²⁺-Chitosan Quaternary Ammonium Salt-g-Poly(acrylicacid) with Efficient Antibacterial Activity [J]. Chem. J. Chinese Universities, 2017, 38(5): 902.
[10]	LI Hong, DU Libo, ZHANG Han, ZHAO Yuming, LIU Yang. New Tanshinone IIA Delivery System Using Chitosan Nanomicelles of Small Size^† [J]. Chem. J. Chinese Universities, 2016, 37(7): 1229.
[11]	LI Zhengzheng, XU Ziyang, GAO Liuyi, ZENG Wei, ZHAO Linlin. Preparation and Characterization of Thermo-sensitive N-Acetyl Glycol Chitosan Hydrogel for Sustained Drug Release^† [J]. Chem. J. Chinese Universities, 2016, 37(12): 2299.
[12]	XIONG Xingquan, JIANG Yunbing, XIAO Shangyun, SHI Lin, SONG Sida. Highly Efficient Synthesis of 1,2,3-Triazoles Catalyzed by Schiff Base Functionalized Chitosan-CuBr Catalyst^† [J]. Chem. J. Chinese Universities, 2016, 37(10): 1863.
[13]	LIU Shuping, LIU Yichun, WANG Wei. Chitosan-assisted WO₃ Ultrathin Film and Electrochromic Performance^† [J]. Chem. J. Chinese Universities, 2015, 36(6): 1202.
[14]	YANG Junxing, WANG Qi, WANG Yuanyuan, HAN Shu, YAO Jiawei, SHAO Siqi, WANG Jinglong, LIU Zhihui, GUO Yupeng. Preparation and in vitro Release of Multilayer Alginate Chitosan Microspheres Loading VEGF and Vancomycin^† [J]. Chem. J. Chinese Universities, 2015, 36(5): 1025.
[15]	ZHANG Huanhuan, CHEN Jiyun, ZHOU Sunying. Preparation of Open Tubular Capillary Electrochromatography Column with Nano-chitosan Coating and Its Application for Basic Proteins Analyzing^† [J]. Chem. J. Chinese Universities, 2015, 36(4): 631.

The Properties and Preparation of Crosslinked Chitosan Films

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments