Studies on Synthesis, Structure and Antitumor Activities of Analogues of Papaver Somniferum Pollen Tridecapeptide

Abstract

Abstract: Five analogues and five segments were designed and synthesized by using solid phase synthesis method according to separated papaver somniferum pollen tridecapeptide with antitumor activities as leading peptide. Their primary secondary structures in solution were determined by CD spectra and their inhibitive activities to human liver and mammary gland cancer cells were assayed by MTT method. The relationship of structure activity was studied and discussed.

Key words: Papaver somniferum pollen, Pollen peptide, Antitumor activity, Analogue, Segment

CLC Number:

O629

TrendMD:

XU Jia-Xi, JIN Sheng . Studies on Synthesis, Structure and Antitumor Activities of Analogues of Papaver Somniferum Pollen Tridecapeptide[J]. Chem. J. Chinese Universities, 1999, 20(5): 722.

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Studies on Synthesis, Structure and Antitumor Activities of Analogues of Papaver Somniferum Pollen Tridecapeptide

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