高等学校化学学报

高等学校化学学报 ›› 2011, Vol. 32 ›› Issue (7): 1488.

• 研究论文 • 上一篇    下一篇

氯乙酸甲酯为萃取剂的液\|液半微萃取与胶束电动色谱耦联富集分离中性化合物

唐婧1, 郑胜彪1, 朱金坤1, 王田霖2   

  1. 1. 安徽科技学院理学院, 凤阳 233100;
    2. 上海大学化学系, 上海 200444
  • 收稿日期:2010-09-25 修回日期:2010-11-29 出版日期:2011-07-10 发布日期:2011-06-02
  • 通讯作者: 唐婧 E-mail:yayajing@shu.edu.cn
  • 基金资助:

    安徽科技学院引进人才基金项目(批准号: ZRC2009239)资助.

Methyl Chloroacetate as Extraction Solvent for Coupling Liquid-liquid Semimicroextraction with Micellar Electrokinetic Chromatography for the Separation of Neutral Compounds with Concentration Enhancement

TANG Jing1*, ZHENG Sheng-Biao1, ZHU Jin-Kun1, WANG Tian-Lin2   

  1. 1. School of Science, Anhui Science and Technology University, Fengyang 233100, China;
    2. Department of Chemistry, Shanghai University, Shanghai 200444, China
  • Received:2010-09-25 Revised:2010-11-29 Online:2011-07-10 Published:2011-06-02
  • Contact: TANG Jing E-mail:yayajing@shu.edu.cn
  • Supported by:

    安徽科技学院引进人才基金项目(批准号: ZRC2009239)资助.

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摘要： 报道了采用氯乙酸甲酯作为液-液半微萃取溶剂与胶束电动色谱耦联，通过萃取剂柱上分解来富集分离中性化合物的方法。选取烷基苯酮类（C8, C10 和C11）作为模型化合物，将水中的烷基苯酮类化合物通过液-液半微萃取进入氯乙酸甲酯相中，氯乙酸甲酯相直接进入胶束电动色谱中分离。对于苯乙酮、苯丁酮和苯戊酮的检出限分别为50，50和100 μg/L（S/N≥3），三者的富集因子达到63～151。本方法只需要有一个毛细管电泳仪而无须特殊设备，省时且操作简便。因此，有很大的潜力用于实际环境样品分析。

关键词: 液-液半微萃取, 胶束电动色谱, 氯乙酸甲酯, 苯酮, 富集

Abstract: This paper reports the use of methyl chloroacetate (MCA) as an extraction solvent for coupling liquid-liquid semimicroextraction (LLsME) with micellar electrokinetic chromatography (MEKC) through on-capillary decomposition for the separation of neutral compounds with concentration enhancement. Alkylphenones of C8, C10 and C11 were chosen as modeling compounds. Aqueous samples of the ?alkylphenones were extracted by LLsME into methyl chloroacetate. The organic phase was directly subjected to separation by MEKC. The detection limits (S/N≥3) were 50, 50 and 100 μg/L (ppb) for butyrophenone, valerophenone and acetophenone in water, respectively, and the concentration factors of the extraction were in a range of 63 to 151-fold in terms of peak area for the three alkylphenones. The method developed has no requirement on any special experimental apparatuses other than a basic CE setup and is time-saving and easy in operation. Therefore, it would be readily acceptable for routine analysis, especially for environmental samples.

Key words: Liquid-liquid semimicroextraction, Micellar electrokinetic chromatography, Methyl chloroacetate, Alkylphenones, Concentration

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