高等学校化学学报

高等学校化学学报 ›› 2002, Vol. 23 ›› Issue (3): 399.

• 研究论文 • 上一篇    下一篇

三(2-甲基-2-苯基丙基)锡氧衍生物的合成与生物活性

张招贵1, 黄艳琴2, 邹阳1, 张树奎2, 谢庆兰2   

  1. 1. 南昌大学化学系, 南昌 330047;
    2. 南开大学元素有机化学国家重点实验室, 天津 300071
  • 收稿日期:2000-12-01 出版日期:2002-03-24 发布日期:2002-03-24
  • 通讯作者: 谢庆兰(1937年出生),男,教授,博士生导师,主要从事金属有机化学的研究.E-mail:xieqinglan@263.net E-mail:xieqinglan@263.net

Studies on the Biological Activities and Synthesis of Tri(2-methyl-2-phenylpropyl)tinoxide Derivatives

ZHANG Zhao-Gui1, HUANG Yan-Qin2, ZOU Yang1, ZHANG Shu-Kui2, XIE Qing-Lan2   

  1. 1. Department of Chemistry, Nanchang University, Nanchang 330047, China;
    2. State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China
  • Received:2000-12-01 Online:2002-03-24 Published:2002-03-24

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被引次数

8

摘要： 合成了17个新的三(2-甲基-2-苯基丙基)锡氧衍生物.利用IR,1H NMR及元素分析确定了化合物的组成,描述了化合物7的结构.部分化合物的生物活性测试结果表明,它们具有很好的杀螨效果,且阴离子配体对生物活性有一定影响.

关键词: 三(2-甲基-2-苯基丙基)锡氧衍生物, 合成, 晶体结构, 杀螨活性

Abstract: Seventeen tri(2-methyl-2-phenylpropyl)tinoxide derivatives were synthesized and characterized by IR, 1H NMR and elemental analysis. Compound 7 crystallizes in the triclinic space group P1 with a=1.3944(6) nm, b=1.4846(6) nm, c=1.8028(7) nm, α=77.777(7)°, β=82.425(8)°, γ=73.581(8)°, V=3.488(2) nm3, Z=4, F(000)=1612, Dc=1.509 g/cm-3. The ω/2θ scan technique was employed to collect data in the range of 1.16°<θ<25.03°. The refinement of structure for 14452 reflections was converged to final R=0.0378, wR=0.1025. The molecular structure consists of fourcoordinated tin atom in a slightly distorted tetrahedral configuration. The bioassay tests showed a high acaricidal activity of some compounds.

Key words: Tri(2-methyl-2-phenylpropyl)tinoxide derivatives, Synthesis, Crystal structure, Acarcidal activity

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