高等学校化学学报

高等学校化学学报 ›› 1990, Vol. 11 ›› Issue (8): 889.

• 研究简报 • 上一篇    下一篇

复合还原剂硼氢化钠/铁盐对腈的还原

林荣辉, 张永敏, 周子牛   

  1. 杭州大学化学系
  • 收稿日期:1988-12-29 出版日期:1990-08-24 发布日期:1990-08-24
  • 通讯作者: 张永敏
  • 基金资助:

    浙江省自然科学基金

Reduction of Nitriles with Combined Reducing Agent——Sodium Borohydride/Iron Salts

Lin Ronghui, Zhang Yongmin, Zhou Zhiniu   

  1. Department of Chemistry, Hangzhou University, Hangzhou
  • Received:1988-12-29 Online:1990-08-24 Published:1990-08-24

PDF (PC)

被引次数

9

摘要： 硼氢化钠是一种温和的选择性还原剂,在一般条件下只能还原醛、酮和酰卤,对其它化合物,如亚砜、腈等则不起作用,因而限制了其应用范围。据文献据道,某些金属盐能有效地提高硼氢化钠的还原能力[1],最近我们报道[2]了硼氢化钠和六水合三氯化铁在还原亚砜为硫醚的反应中,此复合还原剂比其它试剂具有明显的优点,本工作继续研究了硼氢化钠/铁盐还原腈类化合物为相应的伯胺的反应。

关键词: 还原, 腈, 复合还原剂

Abstract: Under mild conditions both aromatic and aliphatic nitriles were reduced to corresponding primary amines by combined reducing agent——sodium borohydride/ferric chloride in moderate yields. The effect of various solvents and metal salts on the reduction were studied. The reaction mechanism was also discussed.

Key words: Reduction, Nitrile, Combined reducing agent

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