Studies on Interaction of Copper Complexes of Cu(phen) 22+ and Cu(bpy) 22+ with 6-Mercaptopurine and Adenine

Abstract

Abstract: In this paper, the interaction of complexes Cu(phen) ₂²⁺ and Cu(bpy) ₂²⁺ with 6-mercaptopurine (6-MP) and adenine were studied by fluorescence, UV-Vis spectroelectrochemical, and spectroelectrochemical methods. Fluorescence and electrochemical results indicated that the complex ratios of copper complexes with 6-MPand adenine are 1:1, and the complex constants of Cu(phen) ₂²⁺ and Cu(bpy) ₂²⁺ with 6-MPare 2.23×10⁴ L/mol and 6.11 ×10⁴ L/mol, with adenine being 1.91×10⁴ L/mol and 5.45×10⁴ L/mol respectively. Spectroelectrochemical behavior of the copper complexes changed obviously in the presence of 6-MP.These results indicated that there are strong interactions of copper complexes with 6-MP.

Key words: 6-Mercaptopurine, Adenine, Copper complex, Fluorescence spectrometry, UV-Vis spectrum, Spectroelectrochemistry

CLC Number:

O614.12

TrendMD:

ZHANG Rong-Li, ZHU Jun-Jie, ZHAO Guang-Chao, CHEN Hong-Yuan . Studies on Interaction of Copper Complexes of Cu(phen) ₂²⁺ and Cu(bpy) ₂²⁺ with 6-Mercaptopurine and Adenine[J]. Chem. J. Chinese Universities, 1998, 19(9): 1363.

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Studies on Interaction of Copper Complexes of Cu(phen) ₂²⁺ and Cu(bpy) ₂²⁺ with 6-Mercaptopurine and Adenine

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