Studies of Caged Bicyclic Phosphates(Ⅴ)——Synthesis of 1-Oxo-1-Phospha-2,6,7-Trioxabicyclo[2,2,2]-4-Substituted Carbonyl Octane

Abstract

Abstract: Caged bicyclic phosphates would be a new type of pesticides because of their unusual mode of bioaction Also they would be widely used as fire-proofing agents, resin-stabilizers and oil-adductsAs a part of our continuing investigation, other thirteen new derivatives of bicyclic phosphate 4a-n were synthesized by the reaction of 1-oxo-1-phospha-2, 6,7-trioxabicyclo[2,2,2]-4-chlorocarbonyl octane 3 with mercaptans, ethanolamine, ethylene amine, and heterocyclic compoundsAll the compounds were confirmed by elemental analysis, IR and ¹H NMR Through studying the spectra of compound 4_j, we infered its possible structureThe MSspectra of some compounds were discussedIt is indicated that higher thioesters have the same bi-rear-rangement as usual estersThe preliminary biological tests show that compound 4_j has a bactericidal activity.

Key words: Caged bicyclic phosphate, Heterocyrlic compound, Mercaptan, Amide

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LI Yu-gui, LI Jian-min, REN Hai-lan, CHEN Li . Studies of Caged Bicyclic Phosphates(Ⅴ)——Synthesis of 1-Oxo-1-Phospha-2,6,7-Trioxabicyclo[2,2,2]-4-Substituted Carbonyl Octane[J]. Chem. J. Chinese Universities, 1992, 13(2): 204.

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Studies of Caged Bicyclic Phosphates(Ⅴ)——Synthesis of 1-Oxo-1-Phospha-2,6,7-Trioxabicyclo[2,2,2]-4-Substituted Carbonyl Octane

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