高等学校化学学报

高等学校化学学报

• 综合评述 • 上一篇    下一篇

从原生到功能：AIE天然产物的发光、改性及应用

尹诗琪1#，郑志刚1#，何心桐1，王世敏1，顾星桂2，王二静1   

  1. 1. 功能材料绿色制备与应用教育部重点实验室，高分子材料湖北省重点实验室，湖北大学材料科学与工程学院 2. 北京软物质科学与工程高精尖创新中心，北京化工大学材料科学与工程学院
  • 收稿日期:2026-01-21 修回日期:2026-03-09 网络首发:2026-03-10 发布日期:2026-03-10
  • 通讯作者: 顾星桂 E-mail:guxinggui@mail.buct.edu.cn
  • 基金资助:
    国家自然科学基金(批准号：52073082，51603063，52173154)资助

Form Protogenesis to Functionalization: Luminescence，Modification and Application of AIE?active Natural Products

YIN Shiqi1#, ZHENG Zhigang1#, HE Xintong1, WANG Shimin1, GU Xinggui2*, WANG Erjing1*   

  1. 1. Key Laboratory for the Green Preparation and Application of Functional Materials, Ministry of Education, Hubei Key Laboratory of Polymer Materials, School of Materials Science and Engineering, Hubei University 2. Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology
  • Received:2026-01-21 Revised:2026-03-09 Online First:2026-03-10 Published:2026-03-10
  • Contact: Xinggui Gu E-mail:guxinggui@mail.buct.edu.cn
  • Supported by:
    Supported by the National Nature Science Foundation of China(Nos. 52073082, 51603063, 52173154)

PDF (PC)

摘要： 历经20多年的发展，聚集诱导发光（aggregation-induced emission, AIE）已成为由中国科学家引领、并在全球范围内掀起研究热潮的一个新兴科学领域.随着全球化石能源的日益枯竭，人类对源于天然的材料需求和高效利用正日益激增.相较于合成染料，源于大自然的天然AIE发光材料具有原料易得、成本低、生物相容性好、种类丰富等优点，近年来引起越来越多关注.这些天然AIE材料已成功应用于化学传感、生物成像、食品检测、肿瘤诊疗等研究中.尽管如此，大多天然AIE发光材料面临结构不易修饰、发光效率低、功能化有限、开发不充分等诸多问题，其应用场景受到一定限制，对其功能化开发的研究有待深入.基于此，本文首先概述了AIE的发光机理，随后按照生物碱、黄酮、香豆素、萜等分类，重点对近年来报道的天然AIE发光材料发光性、结构改性等工作进行分析总结，对其发光机理及应用展开讨论，希望本文能够为未来构建新的生物基高性能AIE发光材料提供借鉴.

关键词: 聚集诱导发光, 分子内运动受限, 天然产物, 功能化

Abstract: Aggregation-induced emission（AIE）has been evolved into an emerging scientific field pioneered by Chinese scientists and now attracting extensive interest worldwide, with the development of AIE study for more than twenty years. With the increasing depletion of global fossil energy, there is a growing demand for AIE materials derived from natural products and an urgent need for their efficient utilization, exemplified by the increasing attention on bioresource-based aggregation-induced emission luminogens due to their merits of wide raw material resources, low cost, high biocompatibility and great diversity. These AIE materials have been used in study of chemosensing, bioimaging, food inspection, tumor theranostics, etc. However, most BioAIE materials still faces the challenges of hard modification, low luminescence efficiency, limited functionalization, insufficient utilization, and limited application sites. In the review, the AIE mechanism behind is outlined. According to the classifications of alkaloids, flavonoids, coumarins and terpenoids, the luminescence properties and structural modifications of recently reported BioAIE materials are analyzed and summarized. And the luminescence mechanism and applications of these materials are discussed. It is hoped that this review could provide insights for the future development of novel efficient BioAIE materials.

Key words: Aggregation-induced emission, Restriction of intramolecular motions, Natural compounds, Functionalization

中图分类号: 

TrendMD: