高等学校化学学报

高等学校化学学报 ›› 2004, Vol. 25 ›› Issue (2): 292.

• 研究简报 • 上一篇    下一篇

(±)-3,5-二羟基-7,4′-二甲氧基二氢黄酮醇和(±)-3,5,7-三羟基-4′-甲氧基二氢黄酮醇的全合成

张应鹏, 李瀛, 薛吉军, 牛颖辉, 吴疆   

  1. 兰州大学应用有机国家重点实验室, 有机化学研究所, 兰州 730000
  • 收稿日期:2002-12-31 出版日期:2004-02-24 发布日期:2004-02-24
  • 通讯作者: 李　瀛(1954年出生),男,教授,博士生导师,从事有机合成化学研究.E-mail;liying@lzu.edu.cn E-mail:liying@lzu.edu.cn
  • 基金资助:

    国家自然科学基金(批准号;20272020)资助

Total Syntheses of (±)-3,5-Dihydroxy-7,4′-dimethoxy-dihydroflavonol and (±)-3,5,7-Trihydroxy-4′-methoxy-dihydroflavonol

ZHANG Ying-Peng, LI Ying, XUE JI-Jun, NIU Ying-Hui, WU Jiang   

  1. State Key Laboratory of Applied Organic Chemistry, Institute of Organic Chemistry, Lanzhou University, Lanzhou 730000, China
  • Received:2002-12-31 Online:2004-02-24 Published:2004-02-24

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关键词: 二氢黄酮醇, 3, 5-二羟基-7, 4&prime, -二甲氧基二氢黄酮醇, 3, 5, 7-三羟基-4&prime, -甲氧基二氢黄酮醇, 全合成

Abstract: Dihydroxy-7,4′-dimethoxy-dihydroflavonol and (±)-3,5,7-trihydroxy-4′-methoxy-dihydroflavonol were found in many medicinal plants, here we describe a concise synthesis route by selective protection, aldol-condensation, 30% H2O2 epoxidation, cyclization and deprotection from2,4,6-trihydroxyacetophone and anisaldehyde.

Key words: Dihydroflavonol, 3,5-Dihydroxy-7,4′-dimethoxy-dihydroflavonol, 3,5,7-Trihydroxy-4′-methoxy-dihydroflavonol, Total synthesis

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