高等学校化学学报 ›› 2003, Vol. 24 ›› Issue (3): 436.

• 论文 • 上一篇    下一篇

宽叶秦岭藤根部的化学成分

谭兴根, 张晓瑢, 彭树林, 廖循, 丁立生   

  1. 中国科学院成都生物研究所, 成都 610041
  • 收稿日期:2002-02-23 出版日期:2003-03-24 发布日期:2003-03-24
  • 通讯作者: 丁立生(1958年出生),男,博士,研究员,博士生导师,主要从事天然有机化学研究.E-mail:lsding@cib.ac.cn E-mail:lsding@cib.ac.cn
  • 基金资助:

    中国科学院生物科技特别支持项目(批准号:STZ-97-3-08)资助

Chemical Constituents from the Roots of Biondia Hemsleyana

TAN Xing-Gen, ZHANG Xiao-Rong, PENG Shu-Lin, LIAO Xun, DING Li-Sheng   

  1. Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China
  • Received:2002-02-23 Online:2003-03-24 Published:2003-03-24

摘要: 通过正相和反相硅胶柱层析从宽叶秦岭藤根部乙醇提取物中分离纯化得到19个化合物,经波谱分析并结合化学方法鉴定了其结构,其中4个为新化合物,它们分别是3,5-二羟基二十烷酸羽扇豆醇酯(3),2-羟甲基-5-甲氧基苯基-O-β-D-吡喃葡萄糖甙(11),Δ5-孕甾烯-3β,20(S)-二醇-20-O-β-D-吡喃葡萄糖基(1→6)-β-D-吡喃葡萄糖甙(18,秦岭藤甙C)和Δ5-孕甾烯-3β,20(S)-二醇-3-O-β-D-吡喃葡萄糖基-20-O-β-D-吡喃葡萄糖基(1→6)-β-D-吡喃葡萄糖甙(19,秦岭藤甙D).

关键词: 宽叶秦岭藤, 化学成分, 3, 5-二羟基二十烷酸羽扇豆醇酯, 2-羟甲基-5-甲氧基苯基-O-&beta, -D-吡喃葡萄糖甙, 秦岭藤甙C, D

Abstract: Nineteen compounds were isolated from the ethanol extract of the roots of Biondia hemsleyana(Warb.) Tsiang through the repeated column chromatography on normal and reversed phase silica gel. By the spectroscopic and chemical evidence, their structures were elucidated as α-amyrin-3β-acetate(1), lupeol 3-hydroxyoctadencanoate(2), lupeol 3,5-dihydroxyeicosanoate(3), cycloeucalenol(4), 4-methoxy salicylic aldehyde(5), 4-methoxy salicylic acid(6), isovanillin(7), scopoletin(8), isovanillic acid(9), cleomiscosin A(10), 2-hydroxymethyl-5-methoxylphenyl-O-β-D-glucopyranoside(11), pregn-4-ene-3,20-dione(12), neridienone(13), daucosterol(14), pregn-5-ene-3β,17α,20α-triol-20-O-β-D-canaropyranoside(15), periplogenin-3-O-β-D-gluco pyranosyl-(1→4)-β-D-cymaropyranoside(16), pregn-5-ene-3β,20(S)-diol-3-O-[2-O-acetyl-β-D-digitalopyranosyl(1→4)-β-D-cymaropyranosyl]-20-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl-(1→4)-β-D-digitalo pyranoside(17), pregn-5-ene-3β,20(S)-diol-20-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside(18, biondianoside C) and pregn-5-ene-3β,20(S)-diol-3-O-[β-D-glucopyranosyl]-20-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside(19, biondianoside D) respectively. All compounds were isolated from this genus for the first time and 3, 11, 18 and 19 were new compounds among them.

Key words: Biondia hemsleyana, Chemical constituent, Lupeol 3,5-dihydroxyeicosanoate, 2-Hydro, xymethyl-5-methoxylphenyl-O-β-D-glucopyranoside, Biondianoside C, D

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