高等学校化学学报

高等学校化学学报 ›› 2003, Vol. 24 ›› Issue (12): 2324.

• 研究简报 • 上一篇    下一篇

聚合物材料表面纳米条纹对生物细胞生长的影响

陆海伟1, 路庆华1,2, 陈万涛3, 徐宏杰1, 印杰1   

  1. 1. 上海交通大学化学化工学院;
    2. 上海交通大学分析测试中心, 上海 200240;
    3. 上海第二医科大学附属第九人民医院口腔颌面外科口外肿瘤生物实验室, 上海 200011
  • 收稿日期:2002-12-06 出版日期:2003-12-24 发布日期:2003-12-24
  • 通讯作者: 路庆华(1965年出生),男,教授,主要从事激光与聚合物相互作用研究.E-mail:qhlu@sjtu.edu.cn E-mail:qhlu@sjtu.edu.cn
  • 基金资助:

    国家自然科学基金(批准号:20004006;60087001);上海市人民政府科技委员会基金(纳米专项)(批准号:0249nm037)资助

Influence of Nanostructured Polymer Surface on Cell Growth

LU Hai-Wei1, LU Qing-Hua1,2, CHEN Wan-Tao3, XU Hong-Jie1, YIN Jie1   

  1. 1. School of Chemistry and Chemical Technology;
    2. Instrumental Analysis Center, Shanghai Jiaotong University, Shanghai 200240, China;
    3. Laboratory of Oncology Biology, Department of Oral and Maxillofacial Surgery Affiliated Ninth People′s Hospital, Shanghai 200011, China
  • Received:2002-12-06 Online:2003-12-24 Published:2003-12-24

PDF (PC)

被引次数

13

关键词: 生物材料, 纳米结构, 细胞培养, PS培养皿, 紫外激光诱导法

Abstract: The nanogrooved surface of polystyrene(PS) petri-dishes was induced by an ultraviolet laser irradiation method. The influence of the surface nanostructure on the growth of the human tongue squamous cells carcinomas (HTSCC) was investigated. Cells cultured on laser-irradiated PS surface show an enhanced attachment and spreading in HTSCC cell culture test, and cell orientation was successfully controlled by selectively treating the PSsurface. We also prove that the nanostructures on polymer surface improved the cell attachment and spreading.

Key words: Biomaterials, Nanostructure, Cell culture, Polystyrene (PS) petri-dish, Ultraviolet laser irradiation method

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