高等学校化学学报

高等学校化学学报 ›› 2002, Vol. 23 ›› Issue (11): 2049.

• 研究简报 • 上一篇    下一篇

钌卟啉[Ru(bpy)2(MPyTPP)Cl]+与DNA作用的研究

梅文杰1, 刘杰1, 李安兴2, 黄绮雯1, 计亮年1   

  1. 1. 中山大学光电材料与技术国家重点实验室, 中山大学化学与化学工程学院;
    2. 中山大学生命科学学院, 广州510275
  • 收稿日期:2001-10-25 出版日期:2002-11-24 发布日期:2002-11-24
  • 通讯作者: 计亮年(1934年出生),男,教授,博士生导师,从事生物无机化学研究.
  • 基金资助:

    国家自然科学基金(批准号:30070188)资助

Investigation on the Interaction of Ruthenated Porphyrin [Ru（bpy）2（MPyTPP）Cl]+ with Calf Thymus DNA

MEI Wen-Jie1, LIU Jie1, LI An-Xing2, HUANG Qi-Wen1, JI Liang-Nian1   

  1. 1. The State Key Laboratory of Optoelectronic Materials and Technologies, College of Chemistry and Chemical Engineering;
    2. College of Life Science, Zhongshan University, Guangzhou 5102752, China
  • Received:2001-10-25 Online:2002-11-24 Published:2002-11-24

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关键词: 钌卟啉, 小牛胸腺DNA, 相互作用

Abstract: The interaction of ruthenated porphyrin [Ru(bpy)2(MPyTPP)Cl]+ with CT-DNA was investigated with UV-Vis and fluorescent spectrum. It is found that [Ru(bpy)2(MPyTPP)Cl]+ binds to CT-DNA with a high affinity.

Key words: Ruthenated porphyrin, Calf thymus DNA, Interaction

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