高等学校化学学报

高等学校化学学报 ›› 2001, Vol. 22 ›› Issue (7): 1147.

• 研究论文 • 上一篇    下一篇

新型含硫三唑类化合物的合成及生物活性研究

陈文彬, 金桂玉   

  1. 南开大学元素有机化学国家重点实验室, 元素有机化学研究所, 天津 300071
  • 收稿日期:2000-05-23 出版日期:2001-07-24 发布日期:2001-07-24
  • 通讯作者: 金桂玉(1935年生),女,教授,博士生导师,主要从事有机合成和农药化学研究,
  • 基金资助:

    国家自然科学基金(批准号:29832050)

Studies on Synthesis and Biological Activities of Novel Triazole Compounds Containing Sulfur

CHEN Wen-Bin, JIN Gui-Yu    

  1. State Key Laboratory of Elemento Organic Chemistry, Institute of Elemento Organic Chemistry, Nankai University, Tianjin 300071, China
  • Received:2000-05-23 Online:2001-07-24 Published:2001-07-24

PDF (PC)

被引次数

68

摘要： 利用1,3-二芳基-2-[(1H NMR-1,2,4-三唑-1-基)-甲基]-2-丙烯-1-酮与取代苯硫酚进行1,4-亲核加成反应,合成了一类新型含硫三唑类化合物,其结构经元素分析、核磁共振谱和红外光谱确证,并对其进行了生物活性的测试,发现它们具有中等程度的抑菌活性和较好的杀虫活性.

关键词: 1, 4-亲核加成反应, 三唑, 合成, 生物活性

Abstract: The novel triazole compounds containing sulfur are synthesized by 1,4-nucleophilic addition-1,3-diaryl-2-[(1H NMR-1,2,4-triazol-1-yl)-methyl]-2 propen-1 one to substituted thiophenol. The structures of these compounds are determined by elemental analyses, 1H NMR and IRspectral data. These compounds are found to possess moderate degree fungicidal and better pesticidal activities by biological assay.

Key words: Nucleophilic addition, Triazole, Synthesis, Biological activities

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