高等学校化学学报 ›› 1997, Vol. 18 ›› Issue (8): 1316.

• 论文 • 上一篇    下一篇

超分子体系中的分子识别研究(Ⅻ)──环糊精及环糊精双核铜配合物对4-取代苯酚的分子识别

刘育, 尤长城, 韩宝航, 李玉梅, 厉斌, 陈荣悌   

  1. 南开大学化学系, 天津 300071
  • 收稿日期:1996-09-18 出版日期:1997-08-24 发布日期:1997-08-24
  • 通讯作者: 刘育, 男, 42岁, 博士, 教授, 博士导师.
  • 作者简介:刘育, 男, 42岁, 博士, 教授, 博士导师.
  • 基金资助:

    国家自然科学基金;天津市自然科学基金;国家教委跨世纪人才基金;天津市教委跨世纪人才基金

Molecular Recognition Study on Supramolecular System (Ⅻ)──Molecular Recognition of4-Substituted Phenols by Cyclodextrins and Binuclear Cu(Ⅱ) Complexes with Cyclodextrins

LIU Yu, YOU Chang-Cheng, HAN Bao-Hang, LI Yu-Mei, LI Bin, CHEN Rong-Ti   

  1. Department of Chemistry, Nankai University, Tianjin 300071
  • Received:1996-09-18 Online:1997-08-24 Published:1997-08-24

摘要: 用分光光度滴定法在25.0℃时测定了不同pH值下α-,β-,γ-环糊精以及1mol/LNaOH水溶液中α-和β-环糊精双核铜配合物与4-取代苯酚形成超分子配合物的稳定常数.化学计量法表明,主体环糊精及环糊精双核铜配合物与客体4-取代苯酚形成了1:1的超分子配合物.从主-客体间的尺寸关系、pH值、多点识别和诱导契合作用等因素讨论了环糊精及环糊精双核铜配合物对客体4-取代苯酚的分子识别机制.结果表明,β-环糊精双核铜配合物对4-取代苯酚具有特殊的键合能力和分子选择性。

关键词: 环糊精, 环糊精双核铜配合物, 分子识别, 4-取代苯酚

Abstract: The spectrophotometric titrations have been performed in aqueous solutions with different pHvalues at 25.0℃ to give the stability constants (IgKs) for inclusion complexa-tion of various 4-substituted phenols with α-, β- and γ- cyclodextrins and binuclear copper (II)-α, β-cyclodextrins complexes. The stoichiometry of the supramolecular complexes formed is 1:1 for all the host cyclodextrins and binuclear copper(II)-cyclodextrins complex-es inclusion complexation with various guest 4-substituted phenols.The molecular recogni-tion mechanism for 4-substituted phenols of the cyclodextrins and binuclear Cu(II) complex-es with cyclodextrins is discussed from the viewpoint of the size/shape-fit, multiple recogni-tion,induced-fit relationship between the host cavity and the guest molecules.The results obtained indicate that the binuclear Cu(II) complex with β-cyclodextrin possesses the spe-cial binding ability and molecular selectivity for 4-substituted phenols.

Key words: Cyclodextrin, Binuclear copper (Ⅱ) complex with cyclodextrin, Molecular recognition, 4-Substituted phenol

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