关键词: 光催化, 烯烃, 硅, 酰基

Abstract: Carbonyl compounds are prevalent in bioactive molecules and organic functional materials, with ketones being particularly important structural motifs. This work focuses on the development of a visible-light photocatalytic three-component difunctionalization of alkenes using silylborates and acyl ammonium salts to access ketone derivatives. Control experiments and DFT calculations revealed that reaction proceeds via a single-electron transfer cascade process between a base/silylboronate complex and an acyl ammonium salt, triggered by a photocatalyst, generating silyl radicals and acyl radical anions. Subsequent sequential coupling with alkenes affords β-silyl ketones. This method features excellent functional group tolerance, mild reaction conditions, and broad substrate scope.

Key words: Photocatalysis, Alkene, Silylation, Acylation