高等学校化学学报 ›› 2021, Vol. 42 ›› Issue (6): 2072.doi: 10.7503/cjcu20210034

• 材料化学 • 上一篇    下一篇

水溶性近红外Ⅱ区荧光Ag2Te量子点的合成

周洁琼, 黄艳, 张志凌, 庞代文, 田智全()   

  1. 武汉大学化学与分子科学学院, 武汉 430072
  • 收稿日期:2021-01-18 出版日期:2021-06-10 发布日期:2021-06-08
  • 通讯作者: 田智全 E-mail:zqtian@whu.edu.cn
  • 基金资助:
    国家自然科学基金(91959103)

Water-soluble Ag2Te Quantum Dots with Emission in the Second Near-infrared Window

ZHOU Jieqiong, HUANG Yan, ZHANG Zhiling, PANG Daiwen, TIAN Zhiquan()   

  1. College of Chemistry and Molecular Sciences,Wuhan University,Wuhan 430072,China
  • Received:2021-01-18 Online:2021-06-10 Published:2021-06-08
  • Contact: TIAN Zhiquan E-mail:zqtian@whu.edu.cn
  • Supported by:
    the National Natural Science Foundation of China(91959103)

摘要:

量子点具有独特的光学性质, 在生物医学领域有着广泛的应用. Ag2Te作为Ⅰ-Ⅵ族量子点中的一员, 因具有生物毒性小和带隙窄等优势而备受关注, 但是目前直接合成水溶性Ag2Te量子点的方法较少, 而且可调节的荧光发射波长范围有限. 本文提出了一种合成荧光发射波长位于近红外Ⅱ区窗口的水溶性Ag2Te量子点的新方法. 该方法以硝酸银为银前体, N-乙酰-L-半胱氨酸为配体, 碲前体利用硼氢化钠还原亚碲酸钠得到, 反应条件温和(室温、 大气氛围)且不涉及有毒的有机试剂, 绿色环保. 通过进一步的阳离子处理钝化其表面缺陷, 可以得到尺寸均一的超小粒径水溶性Ag2Te量子点, 量子点的荧光发射波长为1160 nm, 量子产率为8.0% (以IR26染料为参照). 该方法所合成的Ag2Te量子点具有良好的生物相容性, 注入小鼠体内后能观察到明显的近红外荧光, 具有进一步生物应用的潜力.

关键词: 水溶性, Ag2Te量子点, 荧光, 近红外Ⅱ区窗口

Abstract:

Quantum dots(QDs) have a wide range of applications in the field of biomedicine due to their unique optical properties. Ag2Te, as a member of group Ⅰ-Ⅵ quantum dots, has the advantages of low biological toxicity and narrow band gap, which has attracted the attention of scholars at home and abroad. But currently there are few methods for synthesizing water-soluble Ag2Te quantum dots, and the tunable fluorescence emission wavelength range is limited. This paper presented a new method of preparing water-soluble Ag2Te quantum dots with fluorescence emission in the second near-infrared window(NIR-Ⅱ). This method applied silver nitrate as the silver source and N-acetyl-L-cysteine as the ligand. Sodium tellurite was reduced with sodium borohydride to obtain the tellurium source. The reaction condition was mild, such as room temperature, atmospheric atmosphere, and no toxic organic compounds were involved. Moreover, through cationic treatment, the surface defects of Ag2Te QDs were passivated and ultra-small water-soluble Ag2Te quantum dots with uniform size could be obtained. The fluorescence emission was centered at 1160 nm with a quantum yield of 8.0%(using IR26 dye as reference). The Ag2Te quantum dots synthesized by this method had good biocompatibility, and obvious near-infrared fluorescence could be observed after QDs being injected into mice, showing potential for further biological applications.

Key words: Water-soluble, Ag2Te quantum dots, Fluorescence, The Second near-infrared window

中图分类号: 

TrendMD: