高等学校化学学报 ›› 2013, Vol. 34 ›› Issue (2): 381-385.doi: 10.7503/cjcu20120586

• 有机化学 • 上一篇    下一篇

珠子参化学成分分析

时晓磊1, 王加付2, 姚华2, 张培旭2, 李绪文2, 张海玉3, 金永日2   

  1. 1. 吉林大学军需科技学院, 长春 130062;
    2. 吉林大学化学学院, 长春 130012;
    3. 吉林大学第一医院, 长春 130021
  • 收稿日期:2012-06-20 出版日期:2013-02-10 发布日期:2013-01-21
  • 通讯作者: 金永日,男,博士,博士生导师,主要从事天然药物分析研究.E-mail:jinyr@jlu.edu.cn;张海玉,女,博士,副教授,主要从事腹型过敏性紫癜研究.E-mail:zhanghaiyu1622@yahoo.com.cn E-mail:jinyr@jlu.edu.cn;zhanghaiyu1622@yahoo.com.cn
  • 基金资助:

    国家自然科学基金(批准号: 31201295)资助.

Chemical Constituents of Roots of Panax japonicus C. A. Mey. var. major(Burk.)C. Y. Wu et K. M. Feng

SHI Xiao-Lei1, WANG Jia-Fu2, YAO Hua2, ZHANG Pei-Xu2, LI Xu-Wen2, ZHANG Hai-Yu3, JIN Yong-Ri2   

  1. 1. College of Quartermaster Technology, Jilin University, Changchun 130062, China;
    2. College of Chemistry, Jilin University, Changchun 130012, China;
    3. The First Hospital of Jilin University, Changchun 130021, China
  • Received:2012-06-20 Online:2013-02-10 Published:2013-01-21

摘要:

从珠子参根茎中分离得到7个化合物. 利用核磁共振、 质谱和红外等手段, 并结合其理化性质, 鉴定了其结构, 它们分别是24(R)-珠子参苷R1, 6-O-[β-D-吡喃葡萄糖基(1→2)-β-D-吡喃葡萄糖基]-20-O-[β-D-吡喃葡萄糖基(1→4)-β-D-吡喃葡萄糖基]-20(S)-原人参三醇、 6″-乙酰基-人参皂苷Rd、 人参皂苷Rf、 竹节参皂苷Ⅳa、 人参皂苷Rd和竹节参皂苷Ⅴ. 其中, 24(R)-珠子参苷R1和6-O-[β-D-吡喃葡萄糖基(1→2)-β-D-吡喃葡萄糖基]-20-O-[β-D-吡喃葡萄糖基(1→4)-β-D-吡喃葡萄糖基]-20(S)-原人参三醇为2个新化合物, 6″-乙酰基-人参皂苷Rd 和人参皂苷Rf为首次从珠子参根茎中得到.

关键词: 珠子参, 化学成分, 皂苷, 异核多重键相关谱

Abstract:

Seven compounds were isolated fromthe roots of Panax japonicus C. A. Mey. var. major(Burk.)C. Y. Wu et K. M. Feng. They were purified by chromatographic method. The structures of the compounds were deduced by spectroscopic methods as 24(R)-majoroside R1(1), 6-O-[β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl]-20-O-[β-D-glucopyranosyl-(1→4)-β-D-glucopyranosyl]-20(S)-protopanaxatriol(2), 6″-acetyl-ginsenoside-Rd(3), ginsenoside Rf(4), chikusetsusaponin-Ⅳa(5), ginsenoside Rd(6), Chikusetsusaponin-Ⅴ(7). Among them, 24(R)-majoroside R1 and-O-[β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl]-20-O-[β-D-glucopyranosyl-(1→4)-β-D-glucopyranosyl]-20(S)-protopanaxatriol are new compounds; 6″-acetyl-ginsenoside-Rd and ginsenoside Rf are isolated from Panax japonicus C. A. Mey. var. major(Burk.)C. Y. Wu et K. M. Feng for the first time.

Key words: Panax japonicus C. A. Mey, Chemical constituent, Saponin, Heteronuclear multiple bonding correlation

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