高等学校化学学报 ›› 2012, Vol. 33 ›› Issue (05): 885.doi: 10.3969/j.issn.0251-0790.2012.05.004

• 研究论文: 无机化学 • 上一篇    下一篇

荧光磁性双功能树状分子微球的制备与表征

顾银君1,2, 王秀玲1,2, 赵勤3, 陈恭1, 刘勇健1,2, 张利杰1   

  1. 1. 苏州科技学院化学与生物工程学院, 苏州 215009;
    2. 江苏省环境功能材料重点实验室, 苏州 215009;
    3. 苏州大学材料与化学化工学部, 苏州 215123
  • 收稿日期:2011-09-22 出版日期:2012-05-10 发布日期:2012-05-10
  • 作者简介:刘勇健, 男, 博士, 教授, 主要从事新型功能材料的合成与应用研究. E-mail: yjliu1215@yahoo.com.cn
  • 基金资助:

    国家自然科学基金(批准号: 51103120)和苏州科技学院研究生创新(2011)项目(批准号: SKCX11S_055)资助.

Preparation and Characterization of Bifunctional Fluorescent Magnetic Dendrimer Microspheres

GU Yin-Jun1,2, WANG Xiu-Ling1,2, ZHAO Qin3, CHEN Gong1, LIU Yong-Jian1,2, ZHANG Li-Jie1   

  1. 1. School of Chemical and Biological Engineering, Suzhou 215009, China;
    2. Key Laboratory of Environmental Functional Materials of Jiangsu Province, Suzhou University of Science and Technology, Suzhou 215009, China;
    3. College of Materials Science and Chemical Engineering, Soochow University, Suzhou 215123, China
  • Received:2011-09-22 Online:2012-05-10 Published:2012-05-10

摘要: 采用化学共沉淀法, 以FeCl3·6H2O和FeSO4·7H2O为原料制备了磁性Fe3O4纳米颗粒, 采用树状大分子对其进行修饰, 然后通过树状大分子具有的大量空腔及末端丰富的氨基, 经吸附、 键合, 与大量巯基乙酸修饰的CdSe/CdS量子点连接, 得到三代具有荧光磁性双功能的树状分子微球, 并对其进行结构表征与性能测试. 结果表明: 三代复合后的微球的平均粒径分别为15, 34和49 nm; 一代荧光磁性微球的发光性能最佳, 其量子产率达24.1%; 零代荧光磁性微球磁性能最优, 其饱和磁化强度为15.96 A·m2/kg. 这种具有荧光和磁性的双功能纳米复合微粒有望在免疫检测、 靶向治疗、 荧光追踪和磁性分离等方面得到广泛应用.

关键词: 荧光, 磁性, 树状分子, 纳米粒子

Abstract: Three generations of magnetic and luminescent dendrimer microspheres were prepared. Superparamagnetic Fe3O4 nanoparticles were first prepared by hydrothermal coprecipitation of ferric and ferrous ions, followed by the modification of their surfaces with dendrimers. The surface-modified Fe3O4 nanoparticles were then linked to CdSe/CdS quantum dots(QDs), which were modified with thioglycolic acid to form the Fe3O4/CdSe/CdS fluorescent magnetic nanocomposites through the adsorption and bonding of the amino groups on the surfaces of Fe3O4 and the carboxyl groups on CdSe/CdS QDs. The structure and properties of the nanocompo-sites were characterized by Fourier transform infrared spectrometer(FTIR), elemental analysis(EA), transmission electron microscope(TEM), energy dispersive spectrometer(EDS), vibrating sample magnetometer(VSM), photoluminescence(PL) and UV-Vis spectrameters. The results show that the average size of three generations of nanocomposites are 15, 34 and 49 nm, respectively, the fluorescence property of G1F is the best with a fluorescent quantum yield up to 24.1%, while the magnetic property of G0F is the optimal with a saturation magnetization of 15.96 A穖2/kg. The synthesized bifunctional nanocomposites are expected to be widely used in immune detection, luminescence detection, targeted therapy, magnetic separation and so on.

Key words: Fluorescence, Magnetic property, Dendrimer, Nanoparticles

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