Studies on Synthesis of Monosaccharide Esters Catalyzed by Lipases in Organic Solvents

Abstract

Abstract: The synthesis of monosaccharide ester catalyzed by lipase in organic solvents was studied,where monosaccharides and vinyl acetate or acetic anhydride serve as substrates.Quantitative and qualitative methods for determination of monosacchride ester were developed.The activities of lipases from different sources catalyzing synthesis of monosacchride ester were compared and lipase from Pseudmonus S.P.Lipase(PSL1) was the best.We also studied the selectivity of PSL1 to different monosaccharide substrates and found mannitol is the most efficiency substrate to PSL1 and the conversion can reach 95%.The effects of water content in the system,temperature and lipase concentration on the reaction were studied.

Key words: Lipase, Monosaccharide ester, Organic phase, Esterification

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ZHANG Nian-Xiang, CAO Shu-Gui, DONG Huan, LIU Yan-Bin, REN Yi-Qing, HAN Si-Ping, YANG Hong. Studies on Synthesis of Monosaccharide Esters Catalyzed by Lipases in Organic Solvents[J]. Chem. J. Chinese Universities, 1996, 17(9): 1404.

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Studies on Synthesis of Monosaccharide Esters Catalyzed by Lipases in Organic Solvents

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