Synthesis of Spherical Mesoporous SBA-15  with Abundant Carboxyl and Drug Release Profile

Chem. J. Chinese Universities ›› 2011, Vol. 32 ›› Issue (7): 1478.

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Synthesis of Spherical Mesoporous SBA-15 with Abundant Carboxyl and Drug Release Profile

NIE Xin¹, QU Feng-Yu^1,2*, LI Xiao-Feng¹, LIN Hui-Ming^1,2

1. College of Chemistry and Chemical Engineering,
2. Key Laboratory of Design and Synthesis of Functional Materials and Green Catalysis, Colleges of Heilongjiang Province, Harbin Normal University, Harbin 150025, China

Received:2010-09-19 Revised:2011-04-27 Online:2011-07-10 Published:2011-06-02
Contact: QU Feng-Yu E-mail:qufengyu2010@yahoo.cn
Supported by:
国家自然科学基金(批准号：20871037)资助.

Abstract

Abstract: Mesoporous SBA-15 spheres with abundant carboxyl were synthesized dy a one-step method. The effect of CTES on the morphologies, pore sizes and BET surface areas of mesoporous SBA-15 have been investigated. The samples were characterized by powder X-ray diffraction (XRD), scanning electron microscopy (SEM), nitrogen adsorption/desorption and infrared (IR). The morphologies of as-obtained products are sphere-like shapes. The materials possess highly ordered hexagonal mesoporous structure, and large specific surface area and pore volume, and the pore sizes range from 0.5 to 1 μm. The results show the pore size and the surface area of the materials decrease with the increase of modified dosage, obviously. The assembly and delivery test shows that the material has good assembly and drug delivery profiles. As-synthesized products have potential applications in catalysis, drug delivery and fillings for chromatography analysis.

Key words: carboxyl modified, SBA-15, one-step synthesized, spherical, drug release

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NIE Xin, QU Feng-Yu, LI Xiao-Feng, LIN Hui-Ming. Synthesis of Spherical Mesoporous SBA-15 with Abundant Carboxyl and Drug Release Profile[J]. Chem. J. Chinese Universities, 2011, 32(7): 1478.

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Synthesis of Spherical Mesoporous SBA-15 with Abundant Carboxyl and Drug Release Profile

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