Studies on Relationship Between Structure and Antioxidant ActivityUsing Eigen Value Method

Abstract

Abstract: Antioxidants are of great interest because of their involvement in important biological and industrial process. It′s meaningful to study the quantative structure-activity relationship (QSAR) and design novel, efficient, low-toxicity antioxidant. In this article, using eigen values (EVA) method, the QSAR of a group of antioxidants was firstly studied. Without any experimental parameters, we got a QSAR model that is as good as the one reported earlier. Moreover, it′s the first time to use EVA method to study the relationship between the structure and antioxidant activity. And also we believe that EVA will be an efficient approach to study the relationship of QSAR of antioxidants.

Key words: Antioxidant, QSAR, Eigen value method(EVA)

CLC Number:

O626

TrendMD:

KONG De-Xin, JIANG Tao, YAN Zuo-Wei, GUAN Hua-Shi. Studies on Relationship Between Structure and Antioxidant ActivityUsing Eigen Value Method[J]. Chem. J. Chinese Universities, 2004, 25(4): 713.

References

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