Antioxidant Capacity Evaluation for Traditional Chinese Herbal Medicines Based on Sensitive g-C3N4/P25 Nanocomposite Photoelectrochemical Platform †

doi:10.7503/cjcu20190333

Abstract

Abstract:

Chinese herbal medicines are rich in resources and can be found in various types. The efficacy of some Chinese herbal medicines are closely related to their antioxidant effects. Therefore, the rapid and accurate evaluation of the antioxidant capacity is the foundation for the scientific utilization of Chinese herbal medicine resources. By replacing the conventional titanium dioxide(TiO₂) nanomaterials with the P25(the 25 nm anatase and rutile mixed phase titanium dioxide material), the graphitic carbon nitride(g-C₃N₄)/P25 nanocomposite-based sensitive visible light photoelectrochemical platform has been reported herein. In this system, not only the large planar of g-C₃N₄ can serve as a highly-dispersed carrier for the TiO₂ nanomaterials, but also its highly efficient carrier transport capability can endow the composite material with excellent photoelectronchemical performance. The sensitization effect of g-C₃N₄ with a mass ratio of only 0.5% is the best, and the photocurrent response signal of the composite material can be increased by 4.5-fold when compared with the conventional TiO₂ nanomaterials. A good photoelectrochemical signal response can still be obtained under the open circuit potential, which provides a research basis for the construction of the two-electrode system. In comparison with previous reports, the photoelectrochemical strategy not only greatly simplifies the preparation process and reduces the cost, but also effectively improves the visible light utilization efficiency. This method was used for the first time to evaluate the antioxidant capacity of traditional Chinese herbal medicines which provided a new avenue for quantifying the antioxidant performance evaluation of traditional Chinese herbal medicines.

Key words: Antioxidant, Carbon nitride, Titanium dioxide, Photoelectrochemistry, Traditional Chinese herbal medicine

CLC Number:

O657

TrendMD:

LIANG Zhishan, NI Shuang, DAI Mengjiao, HAN Fangjie, HAN Lipeng, NIU Li, HAN Dongxue. Antioxidant Capacity Evaluation for Traditional Chinese Herbal Medicines Based on Sensitive g-C₃N₄/P25 Nanocomposite Photoelectrochemical Platform ^†[J]. Chem. J. Chinese Universities, 2019, 40(10): 2081.

Figures/Tables 8

Fig.1 Synthetic process of g-C3N4/P25

Fig.2 SEM(A, B) and TEM(C, D) images of g-C3N4(A, C) and g-C3N4/P25(B, D), HRTEM(E) and the selected area Ⅰ expansion(F) images and HAAFF-STEM(G) images of g-C3N4/P25 elemental mapping of C(H), N(I), O(J) and Ti(K) of g-C3N4/P25

Fig.3 XRD patterns of g-C3N4/P25(a) and P25(b)(A), XPS survey spectrum of g-C3N4/P25(B) and high resolution XPS spectra of C1s(C), N1s(D) and Ti2p(E) of g-C3N4/P25

Fig.4 UV-Vis DRS(A) and EIS plots measured of the different proportion(B), curve of the photocurrent as a function of potential(C) and photocurrent responses of xg-C3N4/P25(D) The inset of (B) is the equivalent circuit diagram.

Fig.5 Photocurrent responses(A—C) and corresponding liner calibration(A'—C') of 0.5%g-C3N4/P25 modified ITO electrode upon different concentrations of GA(A, A'), CA(B, B') and CT(C, C') Insets in (A)—(C) are the structural formulas of GA(A), CA(B) and CT(C), respectively.

Fig.6 Interference of 200 times L-threonine glucose and citric acid, 100 times L-glycine L-histidine and fructose, 40 times L-proline with photocurrent response of the 0.5%g-C3N4/P25 a. L-Threonine; b. glucose; c. citric acid; d. L-glycine; e. L-histidine; f. fructose; g. L-proline; h. GA.

Fig.7 Antioxidant capacities of traditional Chinese herbal medicines as found with the PEC sensor, the F-C method and the DPPH method Data are expressed in mg/L for the traditional Chinese herbal medicines(n=3). a. Rhubarb; b. purslane; c. liquorice; d. gold lotus; e. semen cassiae; f. ginger; g. ginkgo leaf; h. semen plantaginis; i. sanguisorba officinalis; j. hawthorn; k. polygonum cuspidatum; l. lycium barbarum; m. lotus leaf; n. ginseng.

Fig.8 Anti-oxidation capacity detection mechanism of g-C3N4/P25 system

References 32

[1]	Kunwar A., Priyadarsini K. I. , Journal of Medical and Allied Sciences, 2011,1(2), 53— 60
[2]	Su G. H., Mi X. S. , Chinese Bulletin of Life Sciences, 2015,27(8), 1070— 1075
	( 苏国辉, 米雪松 . 生命科学, 2015,27(8), 1070— 1075)
[3]	Yang W. J., Li Y. R., Gao H., Wu X. Y. Wang X. L., Wang X. N., Xiang L., Ren D. M., Lou H. X., Shen T. , Journal of Ethnopharmacology, 2018,227, 166— 175
[4]	Jia M., Chen H., Zhao R. H., Chen J. D., Xia Z. N., , Chem. J. Chinese Universities, 2013,34(7), 1629— 1634
	( 贾曼, 陈华, 赵荣华, 陈际达, 夏之宁 . 高等学校化学学报, 2013,34(7), 1629— 1634)
[5]	Song Z. B., Zhu C. L., Shi F. Y., Xue G. P., Zhang D. S. , Chinese Journal of Experimental Traditional Medical Formulae, 2012,18(7), 225— 228
	( 宋志斌, 朱成琳, 师方园, 薛贵平, 张丹参 . 中国实验方剂学杂志, 2012,18(7), 225— 228)
[6]	Zhu C., Huang M., Liang Q. L., Wang Y. M., Hu P., Li P., Zhang H. J., Lu X. G., Luo G. A. , Chem. J. Chinese Universities, 2011,32(7), 1512— 1518
	( 朱超, 黄敏, 梁琼麟, 王义明, 胡坪, 李平, 张浩君, 陆晓光, 罗国安 . 高等学校化学学报, 2011,32(7), 1512— 1518)
[7]	Meng F. L., Su X. T., Zheng Y. N. , Journal of South China Agricultural University, 2013, 4, 553—557
	( 孟凡丽, 苏晓田, 郑毅男 . 华南农业大学学报, 2013,4, 553— 557)
[8]	Bedner M., Duewer D. L. , Anal. Chem., 2011,83(16), 6169— 6176
[9]	Kim M. H., Jang J. H., Oh M. H., Heo J. H. Lee M. W. , Natural Product Research, 2014,28(17), 1409— 1412
[10]	Irakli M. N., Samanidou V. F., Biliaderis C. G., Papadoyannis I. N. , Food Chem., 2012,134(3), 1624— 1632
[11]	Della P. F., Rojas D., Scroccarello A., Del C. M. Ferraro. G., Di M. C., Martuscelli M., Escarpa A., Compagnone D. , Sensors & Actuators B: Chemical, 2019,296, 126651
[12]	Piovesan J. V., Jost C. L., Spinelli A. , Sensors & Actuators B: Chemical, 2015,216, 192— 197
[13]	Novak I., Šeruga M., Komorsky-Lovric' Š. , Food Chem., 2010,122(4), 1283— 1289
[14]	Li Q. M., Wang X. Z., Zhou H. Y., Wei W., Li X. W., Jin Y. R., , Journal of Jilin University(Science Edition), 2010,48(05), 865— 867
	( 李清民, 王晓中, 周洪玉, 魏巍, 李绪文, 金永日 . 吉林大学学报(理学版), 2010,48(05), 865— 867
[15]	Liu X. L., Zhong S. S., Yu H. P., Wu K. G., Chai X. H. , Food and Machinery, 2012,28(4), 110— 112
	( 刘晓丽, 钟少枢, 于泓鹏, 吴克刚, 柴向华 . 食品与机械, 2012,28(4), 110— 112)
[16]	Du Q. Q., Zhang X., Song F. R., Liu Z. Q., Liu S. Y. , Chem. J. Chinese Universities, 2010,31(7), 1332— 1336
	( 杜芹芹, 张旭, 宋凤瑞, 刘志强, 刘淑莹 . 高等学校化学学报, 2010,31(7), 1332— 1336)
[17]	Tao Y. Y., Cai C. B., Shu K. Y., Dong J. F., Xu C. D. , Journal of Henan Agricultural Sciences, 2012,41(5), 53— 55
	( 陶永元, 蔡晨波, 舒康云, 董俊芳, 徐成东 . 河南农业科学, 2012,41(5), 53— 55)
[18]	Fan W., Zhang Q., Wang Y. , Phys. Chem. Chem. Phys., 2013,15(8), 2632— 2649
[19]	Li H. B., Li J., Yang Z. J., Xu Q., Hu X. Y. , Ana. Chem., 2011,83(13), 5290— 5295
[20]	Zhang X., Huo K., Peng X., Xu R., Li P., Chen R., Zheng G., Wu Z., Chu P. K. , Chem. Commun., 2013,49(63), 7091— 7093
[21]	Wang Q., Ruan Y. F., Zhao W. W., Lin P., Xu J. J., Chen H. Y. , Anal. Chem., 2018,90(6), 3759— 3765
[22]	Ma W. G., Han D. X., Gan S. Y., Zhang N. Liu S. W., Wu T. S., Zhang Q. X., Dong X. D., Niu L. , Chem. Commun., 2013,49(71), 7842— 7844
[23]	Ni S., Han F. J., Wang W., Han D. F., Bao Y. Han D. X., Wang H. Y., Niu L. , Sensors & Actuators B: Chemical, 2018,259(15), 963— 971
[24]	Wang L. N., Ma W. G., Gan S. Y., Han D. X., Zhang Q. X., Niu L. , Anal. Chem., 2014,86(20), 10171— 10178
[25]	Wang L. N., Han D. X., Ni S., Ma W. G. Wang W., Niu L. , Chemical Science, 2015,6(11), 6632— 6638
[26]	Wang L. N., Wang D. D., Ni S., Han D. X. Wang W., Niu Li. , Biosensors and Bioelectronics, 2017,94, 107— 114
[27]	Ma W. G., Han D. X., Zhou M., Sun H. Wang L. N., Dong X. D., Niu L., Chemical Science, 2014,5(10), 3946— 3951
[28]	Brandwilliams W., Cuvelier M. E., Berset C. , Food Science and Technology-Lebensmittel-Wissenschaft &Technologie, 1995, ( 28), 25— 30
[29]	Meng Y., Song W., Huang H., Ren Z., Chen S. Y. , J. Am. Chem. Soc., 2014,136(32), 11452— 11464
[30]	Li Y. H., Lv K. L., Ho W. K., Dong F., Wu X. F., Xia Y. , Appl. Catal. B:Environ., 2016,202, 611— 619
[31]	Fernando A., Parajuli S., Alpuche-Aviles M. A. , J. Am. Chem. Soc., 2013,135(30), 10894— 10897
[32]	Hochbaum A. I Yang P. , Chem. Rev., 2010,110(1), 527— 546

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Antioxidant Capacity Evaluation for Traditional Chinese Herbal Medicines Based on Sensitive g-C₃N₄/P25 Nanocomposite Photoelectrochemical Platform ^†

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