Construction of Montmorillonite-modified Carbon Fiber Electrode and ItsIn-vivo Detection of Neurotransmitter

Abstract

Abstract: The construction of montmorillonite-modified carbon fiber electrode is reported. The modified electrode shows a good sensitivity and selectivity due to its accumulation to cations and inhabitation to anions. The detection limit of DAand 5-HTare 16×10^-8 and 1×10^-7 mol/L, respectively, which are more sensitive than Nafion modified electrode.In-vivo voltammetry, the electrode has directly detected the dramatic variation of DAconcentration in a rat brain with decreasing blood supply, while it effectively inhabits the oxidation of electroactive compounds and some neurotransmitter metabolites, such as AA, DOPAC, 5-HIAA.

Key words: Montmorillonite, Modified electrode, In-vivo detection, Neurotransmitter

CLC Number:

O657

TrendMD:

YANG Li-Ju, PENG Tu-Zhi . Construction of Montmorillonite-modified Carbon Fiber Electrode and ItsIn-vivo Detection of Neurotransmitter[J]. Chem. J. Chinese Universities, 2001, 22(2): 197.

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Construction of Montmorillonite-modified Carbon Fiber Electrode and ItsIn-vivo Detection of Neurotransmitter

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