Microenvironmental Effect in the Synergistic Antioxidation of β-Carotene and α-Tocopherol

Abstract

Abstract: The antioxidation and antioxidant synergism of β-carotene(β-C) and α-tocopherol(VE) against free radical initiated peroxidation of linoleic acid have been studied by use ofoxygen uptake method in anionic , non-ionic and.cationic micelles, i.e., sodium dodecylsulfate (SDS), polyoxyethylene diisobutylphenol(Triton X-100) and cetyltrimethylammoniumbromide (CTAB), respectively.The peroxidation was initiated by an azo-initiator, eitherwater-soluble 2, 2' -azobis (2-amidinopropane) dihydrochloride(AAPH) or oil-soluble di-tert-butyl hyponitrite(DBHN).It was found that the antioxidant activity depends significantly onthe microenvironment of the reaction medium and the lipophilicity of the initiator.Althoughβ-carotene alone shows relatively weak antioxidant activity only in case of the DBHN-initiated peroxidastion of linoleic acid in SDSmicelle,it works very well synergistically with VEtosignificantly enhance the inhibition effect of VEfor either AAPHand DBHN-initiated peroxi-dation of linoleic acid in SDSand Triton X-100 micelles.The relationship between theantioxidant activity and the microenvironment is discussed.

Key words: Bioantioxidant, Micelle, Microenvironmental effect, β-Carotene, α-Tocopherol

CLC Number:

O621.16

TrendMD:

LI Zhao-Long, MA Lan-Ping, LIU You-Cheng, LIU Zhong-Li. Microenvironmental Effect in the Synergistic Antioxidation of β-Carotene and α-Tocopherol[J]. Chem. J. Chinese Universities, 1997, 18(11): 1814.

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Microenvironmental Effect in the Synergistic Antioxidation of β-Carotene and α-Tocopherol

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