Chem. J. Chinese Universities ›› 1995, Vol. 16 ›› Issue (11): 1802.

• Articles • Previous Articles     Next Articles

Studies on the Drug Controlled Release Materials of Polyphosphate Containing Tyrosine Ester

FAN Chang-Lie, HU Bin, ZHUO Ren-Xi   

  1. Department of Chemistry, Wuhan University, Wuhan, 430072
  • Received:1994-11-10 Revised:1995-04-30 Online:1995-11-24 Published:1995-11-24

Abstract: Novel polyphosphates containing tyrosine alkyl ester were synthesized by solutionpolycondensation in the presence of catalytic amount of DMAP. The release properties of methotrexate(MXT)from these polyphosphates and their microcapsules including MTX were studied.

Key words: Polyphosphate, Drug controlled release materials, L-Tyrosine, Methotrexate(MTX), Microcapsule

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