Chem. J. Chinese Universities ›› 2017, Vol. 38 ›› Issue (11): 1974.doi: 10.7503/cjcu20170249

• Analytical Chemistry • Previous Articles     Next Articles

Preparation, Characterization and Release Properties of β-Cypermethrin Microcapsules

FENG Jianguo1, YANG Guantian1, YUAN Xiaoyong2, CHEN Qicheng1, SUN Chencheng1, YUAN Shuzhong1,*()   

  1. 1. School of Horticulture and Plant Protection, Yangzhou University, Yangzhou 225009, China
    2. National Navel Orange Engineering Research Center,Gannan Normal University, Ganzhou 341000, China
  • Received:2017-04-19 Online:2017-11-10 Published:2017-10-30
  • Contact: YUAN Shuzhong E-mail:szyuan@yzu.edu.cn
  • Supported by:
    † Supported by the Basic Research Project(Natural Science Foundation for Young Scholars) of Jiangsu Province, China(No.BK20170489), the Ganzhou Major Science and Technology Plan Projects, China(No.[2014]131), the Yangzhou Basic Research Program(Natural Science Foundation)—Science and Technology Project for Youth, China(No.YZ2016104) and the Program of Practice and Inovation Trainng Projects for College Students in Jiangsu Province, China(Nos.201711117053Y, 201511117091X)

Abstract:

The solvent evaporation method was adopted to prepare β-cypermethrin microcapsules, using β-cypermethrin as core material, ethylcellulose as wall materials. The physical and chemical properties of microcapsules were characterized. The effects of process conditions on appearance, mean particle size and distribution, encapsulation efficiency, loading content and controlled release were studied by single factor experiments. The results indicated that emulsifier types and shearing duration time had significant influence on appearance of microcapsules. The particle size and size distribution decreased with the increasing of emulsifier concentration. When the dosage of Tween-80 increased from 4% to 8%, the average particle size of microcapsules decreased from 59.9 μm to 29.8 μm, and the span reduced from 1.21 to 0.72. As the core-wall ratio decreased, there was a gradual increase in both particle size and encapsulation efficiency, but a decrease in loading content. When the core-wall ratio was 1:1.75, the encapsulation efficiency was more than 70%. The most fitted drug release kinetics model was the Ritger-Peppas model(lgQ=lgk+nlgt). For microcapsules with similar mean particle sizes and different loading content, the sample with minimum loading content tended to have a lower release rate and cumulative release rate. For microcapsules with similar loading content and diffe-rent mean particle sizes, the sample with largest size tended to have a lower release rate and cumulative release rate.

Key words: Microcapsules, Solvent evaporation, Particle size, Loading content, Cumulative release

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