MOFs-based Microfluidic Chips for Real-time Online Determination of Multiple Heavy Metal Ions

doi:10.7503/cjcu20230395

Abstract

Abstract:

This study combines the accumulation effects of rich microporous ZIF-8 metal-organic framework（MOF） and the electrochemical technology for the metal ions， and the controllable ability of microfluidic devices for the flowing of solution， to construct a new type of sensor to achieve high-throughput， real-time and rapid detection of multiple metal ion contaminations in the environment. The developed ZIF-8-Nafion/ITO-based microfluidic electrochemical sensors have a good linear relationship for Cd²⁺， Pb²⁺ and Hg²⁺ ions in the concentration range of 0.1—100 μmol/L with the detection limit of 0.055， 0.0025 and 0.0016 μmol/L， respectively（S/N=3）. The microfluidic chips require less sample volume which reduces energy consumption； at the same time， the microfluidic devices made up of polydimethylsiloxane are also expected to realize the function of flexible electrodes， which is important for the integrated and automatic detection of biological and environmental samples using portable and flexible electro- chemical devices.

Key words: Microfluidic, Heavy metal detection, Electrochemical sensor, Metal-organic framework（MOF）

CLC Number:

O657

TrendMD:

CHEN Xiaoping, WANG Xutan, LIU Ning, WANG Qingxiang, NI Jiancong, YANG Weiqiang, LIN Zhenyu. MOFs-based Microfluidic Chips for Real-time Online Determination of Multiple Heavy Metal Ions[J]. Chem. J. Chinese Universities, 2024, 45(2): 20230395.

Figures/Tables 8

References 30

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Sample	Added/（μmol·L^-1）		DPV detected/（μmol·L^-1） Lake Soil		Recovery（%） Lake Soil		AAS Detected/（μmol·L^-1） Lake Soil
Blank	Cd²⁺	0.0	—	—	—	—	—	—
	Pb²⁺	0.0	0.705±0.070	0.482±0.041	—	—	0.725	0.286
	Hg²⁺	0.0	0.133±0.045	0.071±0.033	—	—	0.121	0.062
1	Cd²⁺	5.0	4.81±0.21	5.38±0.36	96.2	108	4.81	5.32
	Pb²⁺	5.0	5.34±0.33	5.31±0.41	107	106	5.32	4.63
	Hg²⁺	5.0	4.82±0.16	4.97±0.56	96.4	99.4	4.76	5.10
2	Cd²⁺	20	18.7±0.2	21.3±1.4	93.6	106	20.4	21.4
	Pb²⁺	20	18.3±0.5	19.2±0.8	91.4	96.0	20.7	18.9
	Hg²⁺	20	19.9±1.0	19.4±0.3	99.9	97.1	19.8	19.6
3	Cd²⁺	50	47.6±1.0	50.7±1.6	95.1	101	49.1	52.0
	Pb²⁺	50	46.6±2.1	51.5±1.9	93.1	103	49.8	48.4
	Hg²⁺	50	50.8±2.7	47.5±3.1	102	95.0	52.1	47.7

Sample	Added/（μmol·L^-1）		DPV detected/（μmol·L^-1） Lake Soil		Recovery（%） Lake Soil		AAS Detected/（μmol·L^-1） Lake Soil
Blank	Cd²⁺	0.0	—	—	—	—	—	—
	Pb²⁺	0.0	0.705±0.070	0.482±0.041	—	—	0.725	0.286
	Hg²⁺	0.0	0.133±0.045	0.071±0.033	—	—	0.121	0.062
1	Cd²⁺	5.0	4.81±0.21	5.38±0.36	96.2	108	4.81	5.32
	Pb²⁺	5.0	5.34±0.33	5.31±0.41	107	106	5.32	4.63
	Hg²⁺	5.0	4.82±0.16	4.97±0.56	96.4	99.4	4.76	5.10
2	Cd²⁺	20	18.7±0.2	21.3±1.4	93.6	106	20.4	21.4
	Pb²⁺	20	18.3±0.5	19.2±0.8	91.4	96.0	20.7	18.9
	Hg²⁺	20	19.9±1.0	19.4±0.3	99.9	97.1	19.8	19.6
3	Cd²⁺	50	47.6±1.0	50.7±1.6	95.1	101	49.1	52.0
	Pb²⁺	50	46.6±2.1	51.5±1.9	93.1	103	49.8	48.4
	Hg²⁺	50	50.8±2.7	47.5±3.1	102	95.0	52.1	47.7

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