Table of Content

10 April 2026, Volume 47 Issue 4

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Preface

点亮聚集体之光，共筑学术丰碑——庆祝唐本忠院士七秩华诞专刊

秦安军, 田文晶, 杨扬

2026, 47(4):  1-2. 

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Content

Cover and Content of Chemical Journal of Chinese Universities Vol.47 No.4(2026)

2026, 47(4):  1-6. 

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Review

Intelligent Response， Precision Activation： Novel Theranostic Strategies of Enzyme-responsive Aggregation-induced Emission Materials in Biomedicine

FANG Jinyu, HUANG Hanwei, SONG Hang, WU Qian, ZHAO Zheng, TANG Ben Zhong

2026, 47(4):  20260009.  doi:10.7503/cjcu20260009

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With the advancement of precision medicine， there is an urgent demand for in situ imaging and targeted therapy with high specificity and high sensitivity. Traditional fluorescent probes are often limited by aggregation-caused quenching effects and frequently suffer from issues such as high background signals， poor photostability， and insufficient specificity. Aggregation-induced emission（AIE） materials， with their unique characteristic of being “off”at the molecular level and “on” in the aggregated state， provide a new strategy for constructing high-performance biological fluorescent probes. Enzymes， serving as key biomarkers in disease processes， exhibit substrate specificity and high efficiency in biocatalytic reactions， making them an ideal trigger mechanism for achieving controllable response， precise fluorescence activation， and signal amplification at disease sites using AIE materials. This review comprehensively reviews the latest research progress in the interdisciplinary frontier of enzyme-responsive AIE materials for novel diagnostic and therapeutic strategies in biomedicine. Based on the physicochemical nature and structural characteristics of aggregates formed after enzyme response， we systematically categorize three molecular design strategies， with a focus on elucidating their design principles， response mechanisms， and significant achievements in the diagnosis and treatment of various major diseases， including tumor imaging and intraoperative navigation， diagnosis and treatment of bacterial and viral infections， diagnosis of neurodegenerative diseases， and theranostics. By enabling controllable “off-on” signal switching and targeted amplification， enzyme-responsive AIE materials demonstrate great potential in improving imaging signal-to-noise ratio， enhancing treatment precision， and achieving synergistic diagnosis and therapy. Finally， we analyze the current challenges in this field and provide an outlook on future development trends， particularly new design paradigms integrated with artificial intelligence.



Research Progress on Hydrogen-bonded Organic Frameworks with Aggregation-induced Emission

YANG Zhan, DENG Huangjun, CHI Zhenguo

2026, 47(4):  20260012.  doi:10.7503/cjcu20260012

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Hydrogen-bonded organic frameworks（HOFs） are an emerging class of porous crystalline materials constructed through intermolecular hydrogen-bond self-assembly. Owing to their high crystallinity， structural tunability， dynamic reversibility， and facile functionalization， HOFs have shown considerable potential in gas adsorption and separation， chemical sensing， and optoelectronic functional materials. However， conventional organic luminophores often suffer from aggregation-caused quenching（ACQ） in the solid state， which limits their luminescent performance. Recently， incorporating aggregation-induced emission（AIE） characteristics into HOFs has emerged as an effective strategy to overcome ACQ. This review summarizes recent advances in AIE-active fluorescent and phosphorescent HOFs， focusing on their structural design， mechanisms， and applications， and briefly discusses current challenges and future perspectives.



Cutting-edge Advances in Raman Imaging Technology and Its Interdisciplinary Research with Aggregate Science

LI Yuting, LUO Liang

2026, 47(4):  20260008.  doi:10.7503/cjcu20260008

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Raman imaging， as a molecular spectroscopy technique， has been widely studied and applied in research fields such as life sciences and food safety due to its excellent specificity and high resolution. However， its development still faces challenges such as weak signals， slow acquisition speed， and insufficient penetration depth. In recent years， the rapid development of aggregate science has provided new insights for addressing these limitations. Aggregation-induced emission（AIE） materials exhibit enhanced signals in the aggregated state， which may compensate for the inherent weak Raman signals. This article reviews the cutting-edge progress of Raman imaging technology and its current status in cross-disciplinary research with aggregate science， emphasizing the strategy of constructing AIE-Raman dual-responsive probes through molecular engineering to achieve functional complementarity between fluorescence localization and Raman quantification， thereby significantly improving detection sensitivity and specificity. These probes have demonstrated single-cell resolution and high spatiotemporal accuracy in applications such as tumor surgical navigation， diagnosis and treatment of drug-resistant bacteria， and dynamic monitoring of organelles. We also analyze the bottlenecks in this field， such as biological safety and the complexity of molecular design， and outline the future development directions， including intelligent responsive probes， artificial intelligence-assisted analysis， and multimodal fusion platforms. The integration of Raman imaging and AIE sheds new light in the field of medical imaging.



Construction of Near-infrared Triggered Organic Photosensitive Materials and Their Applications in Disease Treatment

SUN Yan, ZHU Dongxia

2026, 47(4):  20260002.  doi:10.7503/cjcu20260002

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Phototherapy， mainly including photodynamic therapy（PDT） and photothermal therapy（PTT）， has emerged as a promising non-invasive alternative due to its precision and minimal side effects. Compared with inorganic photosensitive materials， organic photosensitive materials offer advantages in terms of biocompatibility， structural tunability and precise structural purity. However， most clinically approved photosensitizers require activation by visible light（400—700 nm） and the limited tissue penetration depth severely restricts their therapeutic efficacy. In contrast， near-infrared light（NIR， 700—2500 nm） exhibits superior tissue penetration capacity and causes less damage to healthy tissues， making the optimal optical window for biomedical applications. Therefore， the development of high-performance NIR-absorbing organic photosensitive materials is significance. This article syste-matically reviews the molecular design， performance optimization， and biological application strategies of near-infrared organic photosensitive materials， providing a forward-looking perspective for the construction of a new generation of integrated diagnosis and treatment phototherapy platform.



Fluorescent Supramolecular Polymer Networks

REN Aocheng, LI Qingyun, JI Xiaofan

2026, 47(4):  20250390.  doi:10.7503/cjcu20250390

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Supramolecular polymer networks（SPNs） are a class of functional systems formed by cross-linking polymers through dynamic and reversible non-covalent interactions. Their unique structures have driven the development of various functional materials. As an important branch， fluorescent supramolecular polymer networks（FSPNs） significantly expand the variety and functional dimensions of polymer materials by ingeniously combining the dynamic nature of non-covalent interactions with the rich photophysical properties of fluorophores. These systems exhibit broad application prospects in fields such as information storage materials， chemical sensing， and optoelectronic functional materials. Herein， this review summarized the research progress of FSPNs in the past five years， taking the types of non-covalent interactions as the main thread， and looks forward to their future development directions. This review aims to systematically summarize the preparation strategies and application status in this field， providing references for an in-depth understanding of FSPNs and offering valuable insights for the design of advanced fluorescent materials and multifunctional polymer materials.



Article

Novel AIE Fluorescent Probes for Ultrahigh Sensitivity and High Photostability in Lipid Droplets Imaging

GAO Xin, QING Jia, HU Yichen, SHANGGUAN Zhichun, LIANG Tongling, ZHOU Yongsheng, ZHANG Guanxin, ZHANG Deqing

2026, 47(4):  20250410.  doi:10.7503/cjcu20250410

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Two novel aggregation-induced emission（AIE）-active probes， TPA-H and TPA-2F， were designed and synthesized based on a triphenylamine（TPA） core. Systematic characterization demonstrated that both probes exhibit excellent biocompatibility（cell viability>90% at concentrations up to 50 µmol/L） and outstanding LD-targeting specificity with minimal colocalization with other organelles such as mitochondria and lysosomes. During early differentiation of 3T3-L1 adipocytes， both TPA-2F and TPA-H clearly visualized small and nascent LDs that were difficult to be detected with BODIPY， indicating superior imaging sensitivity compared to the existing fluorescent probes for LDs. Moreover， TPA-2F demonstrated exceptional photostability， retaining over 90% of its initial fluorescence intensity after 100 continuous laser scanning cycles， significantly outperforming TPA-H. This work not only provides two high-performance LD imaging tools but also highlights the potential of AIE luminogens（AIEgens） in organelle-specific bioimaging， offering promising avenues for early diagnosis and mechanistic research of lipid-related metabolic diseases.



Side-chain Engineering of “Bridging” Polymer Acceptors with Donor/Acceptor Dual Similarity for High-performance Ternary Organic Solar Cells

LIU Miaomiao, FU Mengran, GAO Die, ZHANG Wanpeng, LIANG Ying, HE Yuanyuan, ZHAO Qiaoqiao, ZHAO Tingxing, LI Hongbo, DING Zicheng, HAN Yanchun

2026, 47(4):  20250324.  doi:10.7503/cjcu20250324

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The morphology of active layer plays a critical role in determining the photovoltaic performance of organic solar cells（OSCs）. However， binary blends often suffer from suboptimal phase separation， which limits the efficiency of OSCs. Herein， two bridging polymer acceptors（PAs）—benzodithiophene-（2-ethylhexyl）oxy（BDT-C₂C₄） and benzodithiophene-octyloxy（BDT-C₈）—are designed and synthesized by combining a benzodithiophene（BDT） unit as the donor moiety［poly（｛4，8-bis［5-（2-ethylhexyl）-4-fluorothiophen-2-yl］benzo［1，2-b：4，5-b'］dithiophene-2，6-diyl｝）｛5，8-bis［4-（2-butyloctyl）thiophen-2-yl］dithieno［3'，2'：3，4］｝， D18］， and a 2，2′-（（2Z，2′Z）-｛［12，13-Bis（2-butyloctyl）-12，13-dihydro-3，9-dinonylthieno［2，3］thieno［3，2-b］pyrrolo［4，5-g］thieno［2，3-b］indole-2，10-diyl］bis（methanylylidene）｝bis（3-oxo-2，3-dihydro-1H-indene-2，1-diylidene））dimalononitrile（Y6） derivative as the acceptor moiety. BDT-C₂C₄ and BDT-C₈ are functionalized with （2-ethylhexyl）oxy and octyloxy side chains on the BDT unit， respectively. Both PAs show complementary absorption and cascaded energy levels with the donor D18 and the acceptor 2，2′-（（2Z，2′Z）-｛［12，13-bis（3-ethylheptyl）-3，9-diundecyl-12，13-dihydro-［1，2，5］thiadiazolo［3，4-e］thieno ［2″，3″∶4′，5′］thieno［2′，3′∶4，5］pyrrolo［3，2-g］thieno［2′，3′∶4，5］thieno［3，2-b］indole-2，10-diyl］bis（methaneylylidene）｝bis（5，6-difluoro-3-oxo-2，3-dihydro-1H-indene-2，1-diylidene））dimalononitrile（N3）， but BDT-C₈ exhibits better compatibility with D18 and N3 compared to BDT-C₂C₄. When incorporated as a third component into the D18∶N3 blend， both PAs improve the active layer morphology. In particular， the D18∶N3∶BDT-C₈ blend shows significantly optimized morphology， featuring reduced phase separation and a fibrous network structure. As a result， the device based on D18∶N3∶BDT-C₈ achieves a power conversion efficiency of 18.18%， significantly higher than that of the device based on D18∶N3（ca.17.37%）. This work presents a compatibilizer strategy for optimizing blend morphology towards high-performance ternary OSCs.



Strategies for Constructing and Organic Afterglow Tuning of Phenothiazine Fused Ring Systems

LIU Peipei, YAN Wanting, YUAN Wentao, LI Qianqian, LI Zhen

2026, 47(4):  20250388.  doi:10.7503/cjcu20250388

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Based on the phenothiazine core， we have synthesized three pentacyclic derivatives（E‑2NAP， Z‑2NAP， and Ph‑ANT）， together with two hexacyclic derivatives（E‑NAP‑ANT and Z‑NAP‑ANT）. In the pentacyclic series， the asymmetric derivative E‑2NAP shows stronger afterglow emission in frozen solution（77 K） than that of the symmetric Z‑2NAP. In the solid state， Ph‑ANT exhibits distinct thermally responsive behavior， with an afterglow lifetime reaching a maximum of 119.68 ms at 293 K， which is primarily attributed to a thermally activated delayed fluorescence（TADF） mechanism. Above 293 K， competition emerges between the TADF pathway and non‑radiative decay channels of triplet excitons， resulting in a reduction in afterglow lifetime. In summary， through rational modulation of the fused‑ring number and substitution positions， this work demonstrates effective adjustment of molecular conformation， solid‑state packing， and room‑temperature afterglow properties， providing important insights for the molecular design of phenothiazine‑based room‑temperature afterglow materials.



Doping-induced Mesoscopic Assembly in Hydrogen-bonded Networks for Phosphorescence Lifetime Modulation

XU Chengshuo, WU Tongyue, GUAN Weijiang, LU Chao

2026, 47(4):  20250395.  doi:10.7503/cjcu20250395

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Room-temperature phosphorescence（RTP） has been attracting more attention in recent years due to its long light-emitting lifetime， large Stokes shift， and sensitivity to the environment， which have important application prospects in the fields of bio-imaging， illumination display， and anti-counterfeiting. Hydrogen-bonded networks are widely employed in the design of solid-state RTP materials owing to their ability to suppress nonradiative transitions and stabilize triplet excited states； however， effective regulations of phosphorescence lifetime in such systems remain challenging. In this work， a hydrogen-bonded assembly based on melamine and isophthalic acid（MA-IPA） was constructed through carboxylic acid-amine hydrogen-bond interactions， and the assembly process was modulated by introducing benzene derivatives bearing different numbers of carboxyl substituents as molecular dopants. The results show that the introduction of dopant molecules does not alter the fundamental building units of the hydrogen-bonded network of MA-IPA but significantly affects the ordered packing mode and mesoscopic structural features. As a consequence， the particle size and specific surface area of the assemblies are effectively regulated， leading to different degrees of oxygen quenching of triplet excitons under ambient conditions. The resulting materials exhibit stable RTP， with phosphorescence lifetime up to 1.7 s. This study provides a viable strategy for the structural regulation of long-lived RTP materials based on hydrogen-bonded networks.



Multi-responsive Hydrogel Featuring Synergistic Regulation of AIE and Mechanical Behaviors via Dynamic Hydrogen Bonding Network

ZHANG Yangdaiyi, SHAO Yan, JIANG Shimei

2026, 47(4):  20250381.  doi:10.7503/cjcu20250381

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A multi-stimuli-responsive hydrogel， P（VI-co-MAAC-NE）， was successfully constructed by covalently integrating the aggregation-induced emission（AIE） moiety（Z）-N-（4-（1-cyano-2-（4-（diethylamino）phenyl）vinyl）- phenyl）methacrylamide（NE） into a dynamic hydrogen-bonding network composed of 1-vinylimidazole（VI） and methacrylic acid（MAAC） groups. The dense hydrogen-bonding network not only provides enhanced mechanical robustness， but also significantly enhances the AIE effect of NE by restricting its molecular motion. Under various external stimuli， the hydrogen bonds within the hydrogel network undergo reversible dissociation and reformation， thus enabling synergistic modulation of the hydrogel’s mechanical properties and luminescence behavior. Specifically， organic solvents disrupt the hydrogen-bonding network and the aggregation of the AIE moiety NE， resulting in macroscopic swelling and fluorescence quenching of the hydrogel. In strongly acidic conditions， protonation of NE molecules suppresses the intramolecular charge transfer（ICT） process， yielding a blue-shifted emission band accompanied by intense blue fluorescence； in highly alkaline environments， deprotonation of carboxyl groups induces hydrogel swelling and disperses NE aggregates， leading to pronounced fluorescence quenching. Moreover， the system exhibits thermally activated shape-memory behavior： heating above the glass transition temperature（T_g： ca. 62 ℃） softens the hydrogel to allow programmable reshaping， and subsequent hydrogen bond reformation at ambient conditions locks in the resultant geometries without sacrificing the hydrogel’s fluorescence performance. By capitalizing on these multi-stimuli-responsive characteristics and shape-memory behavior， the potential of hydrogel P（VI-co-MAAC-NE） for advanced information encryption and anti-counterfeiting applications is demonstrated. This work not only provides a versatile material platform for sensing and information storage， but also offers new insights into the design of intelligent soft materials integrating AIE features with dynamically regulated supramolecular network structures.



Acid/Base and Guest Controlled Delayed Fluorescence and Its Application in Logic Gate

SONG Kuizhu, LONG Yujie, WANG Yaru, WANG Jiaqi, LYU Haiyan, CHEN Chuanfeng

2026, 47(4):  20250382.  doi:10.7503/cjcu20250382

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A delayed fluorescence system regulating the space charge transfer（TSCT） pathway via host-guest interactions and acid-base stimulation is proposed. Within the macrocyclic molecule C［3］A⁃1， an intramolecular TSCT pathway forms between the 3-cyanopyridine acceptor in the cavity and the macrocyclic donor， generating green thermally activated delayed fluorescence（TADF） emission. Upon introduction of the guest 2-cyanopyrazine（2-CP）， host-guest assembly induces a conformational change in the receptor， shutting down the intramolecular TSCT pathway. Simultaneously， a new intermolecular TSCT pathway is established between the guest and the macrocycle sidewall， leading to yellow TADF emission and enabling reversible switching of delayed fluorescence. Furthermore， protonation/deprotonation at the receptor's nitrogen site confers acid-base responsiveness， enabling reversible switching of luminescence. Leveraging these multi-stimulus-responsive properties， a multi-level molecular logic gate was successfully constructed， offering novel insights for designing tunable delayed-fluorescence materials.



Ionization Strategy for the Preparation of a Water-soluble Maleic Anhydride-based Photosensitive Probe and Its Application in High-efficiency Antibacterial Therapy

LI Yin, TANG Ruilin, QU Chao, CHENG Lianghui, HU Yuxi, WU Yuxiang, WANG Zhiming

2026, 47(4):  20250413.  doi:10.7503/cjcu20250413

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The 3，4-diarylmaleic anhydride series derivatives have been applied in biological fluorescence imaging and phototherapy due to their high reactivity with primary amine substances， but their water solubility limitations limit their further biological applications. This paper synthesized a cationic fluorescent probe 2NM-1 from diethyl-aniline via sequential Friedel-Crafts acylation with 1，2-squaroyl chloride， photocatalytic ring expansion， and quaternization with methyl iodide. The probe exhibits pronounced aggregation-induced emission property and good water solubility， and effectively binds to cell membrane through electrostatic interactions， thereby achieving specific fluorescent recognition and imaging of microbes. 2NM-1 displays potent photodynamic antibacterial activity against Gram-positive bacteria and fungi， demonstrating potential for biomedical applications.



Photoexcitation-induced Biomacromolecular Self-assembly

CHENG Jianshuo, YE Wenyan, ZHOU Lulu, LIU Mouwei, LI Zhongyu, TANG Ziran, YU Wanting, ZHU Liangliang

2026, 47(4):  20250398.  doi:10.7503/cjcu20250398

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Under ultraviolet（UV） light， the persulfurated arenes derivative 6SPh-IM exhibits photoexcitation- induced assembly（PEIA） effect. The study further reveals its ability to drive the change of the aggregation state of the biomacromolecule assembly. Under UV irradiation， the aggregated system demonstrates distinct emission spectra， particle size distributions， and circular dichroism（CD） signals， with transmission electron microscopy（TEM） revealing controllable self-assembly morphologies. This strategy of inducing molecular motion upon UV irradiation to modulate system morphology provides novel insights for self-assembly regulation.



Synergistic Luminescence Enhancement Between Sugars and Nonaromatic Amino Acids

CHEN Xiang, ZHANG Qiang, YIN Zhuojie, YUAN Wangzhang

2026, 47(4):  20250400.  doi:10.7503/cjcu20250400

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Inspired by the markedly stronger luminescence of sweet milk powder relative to regular pure milk powder， the synergistic luminescence enhancement effect and associated changes in photophysical properties were systematically investigated through compositional analysis and model reconstruction. Sugar-nonaromatic amino acid doped systems were subsequently constructed， demonstrating a universal synergistic luminescence enhancement effect between sugars（e.g.， sucrose， glucoside） and nonaromatic amino acids（e.g.， lysine， serine）. Experimental results demonstrate that this synergistic effect significantly amplifies luminescence intensity and efficiency（e.g.， the quantum yield of the glycoside-serine doped system increased by over 30-fold）， and also prolongs the phosphorescence lifetime in some cases. Mechanistic analyses combined with theoretical calculations reveal that mixing sugars with nonaromatic amino acids strengthens intermolecular interactions， promotes through-space electron delocalization， and rigidifies conformations. This cooperation enhances both excitation and radiative transition efficiencies of the emissive species， boosting overall luminescent performance. Collectively， these findings provide valuable mechanistic insight and design guidelines for the development of novel luminescent materials based on simple bio-derived components.



Deep-blue Hot Exciton Material Based on Phenanthro［9，10］imidazole Derivative with CIE _y <0.04

GE Shuyuan, FENG Zijun, CHENG Zhuang, LIU Futong, LU Ping

2026, 47(4):  20250403.  doi:10.7503/cjcu20250403

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High-performance deep-blue emitters that meet the BT.2020 standard proposed by the International Telecommunication Union（ITU） for organic light-emitting diodes（OLEDs） remain highly limited. In this work， four deep-blue emitters， PP1M， PP2M， PP3M， and PP4M， are designed and synthesized by connecting methyl- substituted biphenyl groups with classical hot exciton building block of phenanthreneimidazole. The introduction of methyl groups contributes to increase the molecular torsion angle and widen the energy gaps for the four compounds. Through appropriate modulation of substitution site， PP3M achieves the highest photoluminescence quantum yield of 85.3% in neat film. As a result， the PP3M-based device exhibits deep-blue light with external quantum efficiency of 7.2% and suppressed efficiency roll-off. The device also shows a small full width at half maximum of 53 nm and the CIE coordinates locate at（0.16， 0.04）， meeting well with the BT. 2020 standard. The high exciton utilization efficiency is primarily ascribed to the hot exciton pathway. This study provides a reliable insight for the design of efficient deep-blue OLEDs with high color purity.



Chiral AIEgens Based on Calix［4］arene for Enantioselective Recognition of Acids and Amino Acids

MA Huan, DONG Shilong, YANG Juncheng, ZHU Haitao, FENG Haitao

2026, 47(4):  20260049.  doi:10.7503/cjcu20260049

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Two chiral AIEgens derived from calix［4］arene were synthesized， which exhibited prominent enantioselective recognition capabilities. Experimental results demonstrated that these AIEgens could efficiently discriminate between 12 types of chiral acids and amino acids. Notably， upon interaction with D-serine and L-serine， the fluorescence intensity ratio of the system reached 42.0， indicative of exceptional chiral recognition performance. The morphologies of the systems before and after identification were characterized using scanning electron microscopy（SEM）. It was found that different enantiomers induced distinct morphological structures， revealing the intrinsic relationship between the chiral-dependent assembly behavior and the fluorescence response.



Preparation and Mechanochromism Property of a Gold-Copper Cluster Coordination Polymer

HAN Yuchen, ZHANG Meng, YANG Qi, PENG Qiuchen, LI Kai

2026, 47(4):  20260007.  doi:10.7503/cjcu20260007

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An atomic precise gold-copper coordination polymer， ［AuCu（L）₂］ _n （L=phenylacetylene）， was synthesized， which exhibits excellent luminescent properties in the aggregated state. ［AuCu（L）₂］ _n has a one⁃dimensional chain⁃like structure and can be efficiently synthesized by a one⁃pot method at room temperature. Upon grinding， the color of ［AuCu（L）₂］ _n changes from yellow to red， and the emission wavelength red⁃shifts from 550 nm to 620 nm. Under the action of dichloromethane vapor， the red ［AuCu（L）₂］ _n powders can revert to yellow. This reversible change process exhibits excellent fatigue resistance， making ［AuCu（L）₂］ _n suitable for the application in fluorescent anti⁃counterfeiting materials. Mechanistic study shows that ［AuCu（L）₂］ _n transforms from a crystalline state to an amorphous state after grinding. Meanwhile， the original metal⁃metal bonds and a large number of π-π interactions within and between molecules are disrupted， blocking the long-range cluster center luminescence channel， which is the main reason for its luminescence and color change.



Construction and Enantiorecognition Property of Red Emission Chiral Probes Based on Triphenylamine

WU Zeyi, SI Wenni, QI Chunxuan, LI Shuo, FENG Haitao

2026, 47(4):  20250258.  doi:10.7503/cjcu20250258

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The enantiomers show similar physical and chemical properties， while optical， biochemical， and pharmacological activities are often different. Therefore， it is important to selective recognition of one enantiomer from the other. In this work， a pair of chiral cyclic compounds based on triphenylamine， 1，2-dicyanoethylene， and optically pure 1，2-cyclohexanediamine were synthesized. These probes were verified by the means of nuclear magnetic resonance（NMR）， high resolution mass spectroscopies（HRMS）， and single crystal X-ray diffraction（XRD）. Then， the photophysical properties of the probes were investigated. The results indicated that the probes show red emission（622 nm） with high quantum yield（QY up to 35.2%） in the crystal states. The photophysical properties exhibited that the probes are typically aggregation-induced emission compounds. Further， the probes show satisfactory enantiorecognition property， the fluorescence intensity ratio of the complexes were 14.2 to R-/S-1， 2-diaminocyclohexane and 4.28 to R⁃/S-1，2，3，4-tetrahydronaphthalen-2-amine. This work not only enriches the variety of AIE-type cyclic compounds but also extends the emission wavelength of chiral probes. The obtained compound can serve as a simple and convenient measurement tool for enantioselectively recognizing racemic compounds.