Chem. J. Chinese Universities ›› 2020, Vol. 41 ›› Issue (5): 872.doi: 10.7503/cjcu20190684

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Advances in Bacterial Detection Based on Raman Spectroscopy

LI Wenshuai1,3,WU Guorui2,3,ZHANG Xijing3,YUE Aiqin2,DU Weijun2,ZHAO Jinzhong1,*(),LIU Dingbin3,*()   

  1. 1. College of Arts and Sciences
    2. College of Agriculture, Shanxi Agricultural University, Taigu 030800, China
    3. College of Chemistry and State Key Laboratory of Medicinal Chemical Biology,Nankai University, Tianjin 300071, China
  • Received:2019-12-17 Online:2020-05-10 Published:2020-02-26
  • Contact: Jinzhong ZHAO,Dingbin LIU E-mail:zhaojinzhongnd@126.com;liudb@nankai.edu.cn
  • Supported by:
    † Supported by the National Natural Science Foundation of China(21775075);† Supported by the National Natural Science Foundation of China(21977053)

Abstract:

Bacteria is a kind of microorganism that is closely related to human activities, and its rapid and highly sensitive detection is very important for the prevention and control of major infectious diseases. In this paper, the basic principle of Raman spectroscopy for bacterial detection is introduced, and three main methods of Raman spectroscopy for bacterial detection, including bacterial composition detection, bacterial metabolites detection and Raman probe labeling based detection mode, are reviewed and compared. Finally, the development prospect of Raman spectroscopy in the field of bacterial detection was prospected, and five suggestions were put forward.

Key words: Raman spectroscopy, Bacterial detection, Surface-enhanced Raman spectroscopy

CLC Number: 

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