Recent Advances on Polyoxometalates as Metallodrug Agents for Alzheimer’s Disease †

doi:10.7503/cjcu20190714

Abstract

Abstract:

Alzheimer’s disease(AD) is a progressive neurodegenerative disorder characterized by cognitive dysfunction and memory loss. Although the exact pathogenesis of AD remains unclear, recent evidences have demonstrated that the accumulation and deposition of β-amyloid peptide(Aβ) is a key step in AD pathogenesis. Polyoxometalates(POMs) have the merits of adjustable structures, ease of preparation, and low cost, and thus have shown promising in AD treatment. Hence, recent advances on the POMs as a novel AD metallodrug agent are summarized.

Key words: Alzheimer’s disease, Polyoxometalates, β-Amyloid

CLC Number:

O614.6

TrendMD:

MA Mengmeng, QU Xiaogang. Recent Advances on Polyoxometalates as Metallodrug Agents for Alzheimer’s Disease ^†[J]. Chem. J. Chinese Universities, 2020, 41(5): 884.

Figures/Tables 9

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