Chem. J. Chinese Universities ›› 2021, Vol. 42 ›› Issue (11): 3468.doi: 10.7503/cjcu20210425

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Advances in Bacteria Biosensing Based on Molecular Recognition

ZHANG Xiaorong1, CHEN Lanlan2(), HU Shanwen1()   

  1. 1.Department of Health Inspection and Quarantine,School of Public Health,Fujian Medical University,Fuzhou 350122,China
    2.College of Chemistry,Fuzhou University,Fuzhou 350108,China
  • Received:2021-06-22 Online:2021-11-10 Published:2021-11-10
  • Contact: CHEN Lanlan,HU Shanwen E-mail:llchen@fzu.edu.cn;shanwenhu@fjmu.edu.cn
  • Supported by:
    the National Natural Science Foundation of China(21804064)

Abstract:

Bacteria widely exist in the natural environment and are closely related to human health. The identification and detection of bacteria are of great significance for public health and medical health. Recently, more attention has been attracted in molecular recognition-based bacteria biosensing with high specificity and sensitivity. Herein, recent progresses of bacterial detection based on molecular recognition are reviewed. Molecular recognition methods are classified into three kinds of interactions: antibody-antigen immune interaction, nucleic acid recognition based on Watson-Crick base-pairing, and aptamer-ligand interaction. Finally, the existing bottlenecks of bacterial detection related research are summarized, and the potential of this field is inspiring.

Key words: Molecular recognition, Bacterial detection, Nucleic acid probe, Immune recognition, Aptamer

CLC Number: 

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