Chem. J. Chinese Universities ›› 2014, Vol. 35 ›› Issue (6): 1348.doi: 10.7503/cjcu20131095

• Polymer Chemistry • Previous Articles     Next Articles

Synthesis and Solution Properties of CS-g-PLGA Graft Polyampholytes

WEI Zhaojun1, CHEN Ye1, WANG Dongmei2, FANG Wenxiang1, CHEN Tao1,*(), ZHANG Suning3,*()   

  1. 1. Shanghai Key Laboratory of Advanced Polymeric Materials, School of Materials Science and Engineering,East China University of Science and Technology, Shanghai 200237, China
    2. Dalian Honsen Fire-Tech Co. Ltd., Dalian 116023, China
    3. School of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai 200235, China
  • Received:2013-11-13 Online:2014-06-10 Published:2014-03-24
  • Contact: CHEN Tao,ZHANG Suning E-mail:tchen@ecust.edu.cn;zsn@sit.edu.cn
  • Supported by:
    † Supported by the National Natural Science Foundation of China(No.20974032)

Abstract:

The graft polyampholytes containing a chitosan backbone and poly(L-glutamic acid) branches, i.e. CS-g-PLGA(CGA), with different compositions were synthesized. The molecular architecture and the composition of CGA were characterized. The influences of environmental conditions, such as pH value, ionic strength and ionic types, on the aqueous solution properties of CGAs were investigated. The results show that the isoelectric point(IEP) of CGA shifts to higher pH values with increasing the ionic strength. The larger the ion hydration radius is, the less it influences the IEP. The CGA with approximative amino and carboxyl contents is more sensitive to the variation of ionic strength. Moreover, CGAs exhibit notable pH responsibility to form reversible aggregates in acidic and alkaline solutions, respectively. The stability of the aggregates is found to be improved by increasing the length of PLGA branches for CGAs with similar amino content. The hydrodynamic radii of the aggregates depend on the charge density on CS backbone in acidic solutions and increase with increasing PLGA length in alkaline solutions.

Key words: Polyampholyte, Graft copolymer, Chitosan, Poly(L-glutamic acid), Stimuli-responsive property

CLC Number: 

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