高等学校化学学报

高等学校化学学报

• 研究论文 • 上一篇    下一篇

新型双核配合物的形成及荧光性质研究

张黔玲1, 刘剑洪1, 任祥忠1, 张培新1, 王芳1, 李翠华1, 刘建忠2, 计亮年2   

    1. 深圳大学师范学院化学与生物学系, 深圳 518060;
    2. 中山大学教育部基因工程重点实验室, 生命科学学院, 广州 510275
  • 收稿日期:2006-02-20 修回日期:1900-01-01 出版日期:2006-10-10 发布日期:2006-10-10
  • 通讯作者: 刘剑洪

Formation and Luminescent Properties of New Heterobimetallic Complexes

ZHANG Qian-Ling1, LIU Jian-Hong1, REN Xiang-Zhong1, ZHANG Pei-Xin1, WANG Fang1, LI Cui-Hua1, LIU Jian-Zhong2, JI Liang-Nian2   

    1. Department of Chemistry and Biology, Normal College, Shenzhen University, Shenzhen 518060, China;
    2. The Key Laboratory of Gene Engineering of Ministry of Education, Colledge of Life Science, Zhongshan University, Guangzhou 510275, China
  • Received:2006-02-20 Revised:1900-01-01 Online:2006-10-10 Published:2006-10-10
  • Contact: LIU Jian-Hong

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被引次数

35

摘要： 利用光谱学方法研究了[Ru(bpy)2TPPHZ]2+(TPPHZ=四吡啶[3,2-a: 2',3'-c: 3",2"-h: 2'",3'"-j]吩嗪)和[Ru(bpy)2ODHIP]2+(ODHIP=3,4-二羟基-咪唑并[4,5-f][1,10]邻菲咯啉)与Ni2+的配位情况及配位后的荧光性质变化, 探讨了配合物与Ni2+配位形成双核配合物后与DNA的作用机制变化. 结果表明, [Ru(bpy)2TPPHZ]2+和[Ru(bpy)2ODHIP]2+均可与Ni2+配位, 形成双核配合物[Ru(bpy)2(TPPHZ)Ni]4+和[Ru(bpy)2(ODHIP)Ni]4+, 配合物的荧光强度随着Ni2+浓度的增加而减弱. 与DNA作用后, 配合物仍可与Ni2+配位形成双核配合物, [Ru(bpy)2(TPPHZ)Ni]4+的荧光几乎完全消失, 同时配合物与DNA保持插入模式作用, 而配合物[Ru(bpy)2(ODHIP)Ni]4+与DNA的作用则由沟面结合改为插入结合, 同时配合物的荧光减弱.

关键词: 多吡啶钌(Ⅱ)配合物, DNA, Ni2+, 荧光, 插入结合

Abstract: The formation of new heterobimetallic complexes obtained via the coordination reactions of [Ru(bpy)2TPPHZ]2+(TPPHZ=tetrapyrido[3,2-a: 2',3'-c: 3",2"-h: 2'",3'"-j]phenazine) and [Ru(bpy)2ODHIP]2+(ODHIP=3,4-dihydroxyl-imidazo[4,5-f][1,10]phenanthroline) with Ni2+ were investigated by spectroscopic methods. The DNA-binding and luminescent properties of the complexes after coordinating with Ni2+ were also studied. The experimental results indicate that both [Ru(bpy)2TPPHZ]2+ and [Ru(bpy)2ODHIP]2+ could coordinate with Ni2+ to form the heterobimetallic
complexes [Ru(bpy)2•(TPPHZ)Ni]4+ and [Ru(bpy)2(ODHIP)Ni]4+. The emission intensity of the complexes decreased with increasing the amounts of Ni2+. After binding to DNA, both complexes could coordinate with Ni2+ to form the heterobimetallic complexes. [Ru(bpy)2(TPPHZ)Ni]4+ kept binding to DNA by intercalation, and the luminescence of complex almost disappeared at n(Ni)/n(Ru)=1. While the binding mode of [Ru(bpy)2•(ODHIP)Ni]4+ changed from groove binding to intercalation, and the emission intensity of the complex decreased.

Key words: Polypyridyl ruthenium(Ⅱ) complex, DNA, Ni2+, Luminescence, Intercalation

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