高等学校化学学报

高等学校化学学报 ›› 1995, Vol. 16 ›› Issue (10): 1555.

• 论文 • 上一篇    下一篇

α-羰基-α-(1H-1,2,4-三唑-1-基)乙烯基芳基酮衍生物的合成及生物活性研究

李正名, 黄震年   

  1. 南开大学元素有机化学研究所, 天津, 300071
  • 收稿日期:1994-10-25 修回日期:1995-03-09 出版日期:1995-10-24 发布日期:1995-10-24
  • 通讯作者: 李正名,男,64岁,教授.
  • 作者简介:李正名,男,64岁,教授.
  • 基金资助:

    国家自然科学基金

Synthesis of α-Oxo-α-(1H-1,2,4-triazo-1-yl) Ketene N,S-Acetals and Their Biological Activities

LI Zheng-Ming, HUANG Zhen-Nian   

  1. Institute of Elemento-Organic Chemistry Nankai University, Tianjin, 300071
  • Received:1994-10-25 Revised:1995-03-09 Online:1995-10-24 Published:1995-10-24

PDF (PC)

摘要： α-(1H-1,2,4-三唑-1-基)取代苯乙酮与异硫氰酸苯酯在强碱条件下经缩合、卤化后得到含三唑的烯酮氮硫缩醛化合物1.该化合物与各种卤代物反应,形成了包括五元、六元杂环的缩合产物。部分结构具有一定的植物生长调节活性。

关键词: 1H-1, 2, 4-三唑, 烯酮缩醛, 合成, 生物活性

Abstract: The reaction of α-(1H-1,2,4-Triazol-1-yl) substituted acetophenone with isothiocyanate in the presence of a base and subsequent alkylation afforded twenty-six new α-ox-oketene N,S-acetals containing 1H-1,2,4-Triazole. Their structures were confirmed by IR,1HNMR, elementary analysis. The preliminary biological test showed that some componds obtained have plant-regulatory activities.

Key words: 1H-1,2,4-Triazole, Ketene acetal, Synthesis, Biological activities

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